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Index > Protein center > Cyp2d26(Gene name) > Rat
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  • Cyp2d26 (Gene name),
  • Cytochrome P450 2D26 (Protein name ),  CP2DQ_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Cyp2d26(Cyp2d-26;Cyp2d2);
    Protein name:
    Cytochrome P450 2D26;
    Alternative:
    Cytochrome P450-CMF2;CYPIID26;Debrisoquine 4-hydroxylase;Cytochrome P450-DB2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    500
    Sequence:
    50:
    MGLLIGDDLW | AVVIFTAIFL | LLVDLVHRHK | FWTAHYPPGP | VPLPGLGNLL | 
    100:
    QVDFENMPYS | LYKLRSRYGD | VFSLQIAWKP | VVVINGLKAV | RELLVTYGED | 
    150:
    TADRPLLPIY | NHLGYGNKSK | GVVLAPYGPE | WREQRRFSVS | TLRDFGVGKK | 
    200:
    SLEQWVTEEA | GHLCDTFAKE | AEHPFNPSIL | LSKAVSNVIA | SLVYARRFEY | 
    250:
    EDPFFNRMLK | TLKESFGEDT | GFMAEVLNAI | PILLQIPGLP | GKVFPKLNSF | 
    300:
    IALVDKMLIE | HKKSWDPAQP | PRDMTDAFLA | EMQKAKGNPE | SSFNDENLRL | 
    350:
    VVIDLFMAGM | VTTSTTLSWA | LLLMILHPDV | QRRVHEEIDE | VIGQVRRPEM | 
    400:
    ADQARMPFTN | AVIHEVQRFA | DIVPTNIPHM | TSRDIKFQGF | LIPKGTTLIP | 
    450:
    NLSSVLKDET | VWEKPLRFHP | EHFLDAQGNF | VKHEAFMPFS | AGRRACLGEP | 
    500:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 2D26
    ELISA Kit for Rat Cytochrome P450 2D26
    CLIA Kit for Rat Cytochrome P450 2D26
    CLIA Kit for Rat Cytochrome P450 2D26
    Polyclonal Antibody for Rat Cytochrome P450 2D26
    Polyclonal Antibody for Rat Cytochrome P450 2D26
    Monoclonal Antibody for Rat Cytochrome P450 2D26
    Monoclonal Antibody for Rat Cytochrome P450 2D26
    Protein for Rat Cytochrome P450 2D26
    Protein for Rat Cytochrome P450 2D26

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Debrisoquine 4-hydroxylase: characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism."
      Gonzalez F.J. , Matsunaga T. , Nagata K. , Meyer U.A. , Nebert D.W. , Pastewka J. , Kozak C.A. , Gillette J. , Gelboin H.V. , Hardwick J.P.
      DNA6:149-161(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats."
      Matsunaga E. , Zanger U.M. , Hardwick J.P. , Gelboin H.V. , Meyer U.A. , Gonzalez F.J.
      Biochemistry28:7349-7355(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Four species of cDNAs for cytochrome P450 isozymes immunorelated to P450C-M/F encode for members of P450IID subfamily, increasing the number of members within the subfamily."
      Ishida N. , Tawaragi Y. , Inuzuka C. , Sugita O. , Kubota I. , Nakazato H. , Noguchi T. , Sassa S.
      Biochem. Biophys. Res. Commun.156:681-688(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site."
      Matsunaga E. , Umeno M. , Gonzalez F.J.
      J. Mol. Evol.30:155-169(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    5. 5.
      "Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity."
      Wan J. , Imaoka S. , Chow T. , Hiroi T. , Yabusaki Y. , Funae Y.
      Arch. Biochem. Biophys.348:383-390(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
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