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Index > Protein center > Cyp2e1(Gene name) > Rat
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  • Cyp2e1 (Gene name),
  • Cytochrome P450 2E1 (Protein name ),  CP2E1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Cyp2e1(Cyp2e;Cyp2e-1);
    Protein name:
    Cytochrome P450 2E1;
    Alternative:
    CYPIIE1;1.14.13.n7;4-nitrophenol 2-hydroxylase);Cytochrome P450RLM6;Cytochrome P450-J;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    493
    Sequence:
    50:
    MAVLGITIAL | LVWVATLLVI | SIWKQIYNSW | NLPPGPFPLP | ILGNIFQLDL | 
    100:
    KDIPKSFTKL | AKRFGPVFTL | HLGSRRIVVL | HGYKAVKEVL | LNHKNEFSGR | 
    150:
    GDIPVFQEYK | NKGIIFNNGP | TWKDVRRFSL | SILRDWGMGK | QGNEARIQRE | 
    200:
    AQFLVEELKK | TKGQPFDPTF | LIGCAPCNVI | ADILFNKRFD | YNDKKCLRLM | 
    250:
    SLFNENFYLL | STPWIQLYNN | FADYLRYLPG | SHRKIMKNVS | EIKQYTLEKA | 
    300:
    KEHLQSLDIN | CARDVTDCLL | IEMEKEKHSQ | EPMYTMENVS | VTLADLFFAG | 
    350:
    TETTSTTLRY | GLLILMKYPE | IEEKLHEEID | RVIGPSRVPA | VRDRLDMPYM | 
    400:
    DAVVHEIQRF | INLVPSNLPH | EATRDTVFQG | YVIPKGTVVI | PTLDSLLYDS | 
    450:
    HEFPDPEKFK | PEHFLNENGK | FKYSDYFKAF | SAGKRVCVGE | GLARMELFLL | 
    493:
    LSAILQHFNL | KSLVDPKDID | LSPVTVGFGS | IPPQFKLCVI | PRS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 2E1
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    ELISA Kit for Rat Cytochrome P450 2E1
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    ELISA Kit for Rat Cytochrome P450 2E1
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    ELISA Kit for Rat Cytochrome P450 2E1
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    ELISA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    CLIA Kit for Rat Cytochrome P450 2E1
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Cytochrome P450 2E1
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    Packing:
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    Polyclonal Antibody for Rat Cytochrome P450 2E1
    Polyclonal Antibody for Rat Cytochrome P450 2E1
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    P0988Rb-m
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    Polyclonal Antibody for Rat Cytochrome P450 2E1
    Polyclonal Antibody for Rat Cytochrome P450 2E1
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    Polyclonal Antibody for Rat Cytochrome P450 2E1
    Polyclonal Antibody for Rat Cytochrome P450 2E1
    Polyclonal Antibody for Rat Cytochrome P450 2E1
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    P0988Rb-h
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    Packing:
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    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Monoclonal Antibody for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1
    Protein for Rat Cytochrome P450 2E1

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    References
    1. 1.
      "Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme."
      Song B.-J. , Gelboin H.V. , Park S.-S. , Yang C.S. , Gonzalez F.J.
      J. Biol. Chem.261:16689-16697(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation."
      Umeno M. , Song B.-J. , Kozak C. , Gelboin H.V. , Gonzalez F.J.
      J. Biol. Chem.263:4956-4962(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Liver.
    3. 3.
      "The complete coding sequence of the rat brain cytochrome P450 2E1."
      Yoo M. , Shin S.W.
      Submitted (1998-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: Sprague-Dawley.
      tissue: Brain.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    5. 5.
      "Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes."
      Favreau L.V. , Malchoff D.M. , Mole J.E. , Schenkman J.B.
      J. Biol. Chem.262:14319-14326(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-35
      tissue: Liver.
    6. 6.
      "Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation."
      Imaoka S. , Terano Y. , Funae Y.
      Arch. Biochem. Biophys.278:168-178(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-20
      tissue: Liver.
    7. 7.
      "Molecular cloning of a cDNA for rat diabetes-inducible cytochrome P450RLM6: hormonal regulation and similarity to the cytochrome P4502E1 gene."
      Richardson T.H. , Schenkman J.B. , Turcan R. , Goldfarb P.S. , Gibson G.G.
      Xenobiotica22:621-631(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 100-463
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