Protein name:
Cytochrome P450 2U1 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Microsome membrane
Protein Attributes:
50:
MSSPGPSQPP | AEDPPWPARL | LRAPLGLLRL | DPSGGALLLC | GLVALLGWSW |
100:
LRRRRARGIP | PGPTPWPLVG | NFGHVLLPPF | LRRRSWLSSR | TRAAGIDPSV |
150:
IGPQVLLAHL | ARVYGSIFSF | FIGHYLVVVL | SDFHSVREAL | VQQAEVFSDR |
200:
PRVPLISIVT | KEKGVVFAHY | GPVWRQQRKF | SHSTLRHFGL | GKLSLEPKII |
250:
EEFKYVKAEM | QKHGEDPFCP | FSIISNAVSN | IICSLCFGQR | FDYTNSEFKK |
300:
MLGFMSRGLE | ICLNSQVLLV | NICPWLYYLP | FGPFKELRQI | EKDITSFLKK |
350:
IIKDHQESLD | RENPQDFIDM | YLLHMEEERK | NNSNSSFDEE | YLFYIIGDLF |
400:
IAGTDTTTNS | LLWCLLYMSL | NPDVQEKVHE | EIERVIGANR | APSLTDKAQM |
450:
PYTEATIMEV | QRLTVVVPLA | IPHMTSENTV | LQGYTIPKGT | LILPNLWSVH |
500:
RDPAIWEKPE | DFYPNRFLDD | QGQLIKKETF | IPFGIGKRVC | MGEQLAKMEL |
544:
FLMFVSLMQS | FAFALPEDSK | KPLLTGRFGL | TLAPHPFNIT | ISRR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Bovine
ELISA Kit for Human Cytochrome P450 2U1
ELISA Kit for Human Cytochrome P450 2U1
ELISA Kit for Human Cytochrome P450 2U1
ELISA Kit for Human Cytochrome P450 2U1
CLIA Kit for Human Cytochrome P450 2U1
CLIA Kit for Human Cytochrome P450 2U1
CLIA Kit for Human Cytochrome P450 2U1
CLIA Kit for Human Cytochrome P450 2U1
Polyclonal Antibody for Human Cytochrome P450 2U1
Polyclonal Antibody for Human Cytochrome P450 2U1
Polyclonal Antibody for Human Cytochrome P450 2U1
Polyclonal Antibody for Human Cytochrome P450 2U1
Monoclonal Antibody for Human Cytochrome P450 2U1
Monoclonal Antibody for Human Cytochrome P450 2U1
Monoclonal Antibody for Human Cytochrome P450 2U1
Monoclonal Antibody for Human Cytochrome P450 2U1
Protein for Human Cytochrome P450 2U1
Protein for Human Cytochrome P450 2U1
Protein for Human Cytochrome P450 2U1
Protein for Human Cytochrome P450 2U1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids."
Chuang S.S.
,
Helvig C.
,
Taimi M.
,
Ramshaw H.A.
,
Collop A.H.
,
Amad M.
,
White J.A.
,
Petkovich M.
,
Jones G.
,
Korczak B.
J. Biol. Chem.279:6305-6314(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue :
Thymus .
2.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
6.
"Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia."
Tesson C.
,
Nawara M.
,
Salih M.A.
,
Rossignol R.
,
Zaki M.S.
,
Al Balwi M.
,
Schule R.
,
Mignot C.
,
Obre E.
,
Bouhouche A.
,
Santorelli F.M.
,
Durand C.M.
,
Oteyza A.C.
,
El-Hachimi K.H.
,
Al Drees A.
,
Bouslam N.
,
Lamari F.
,
Elmalik S.A.
,
Kabiraj M.M.
,
Seidahmed M.Z.
,
Esteves T.
,
Gaussen M.
,
Monin M.L.
,
Gyapay G.
,
Lechner D.
,
Gonzalez M.
,
Depienne C.
,
Mochel F.
,
Lavie J.
,
Schols L.
,
Lacombe D.
,
Yahyaoui M.
,
Al Abdulkareem I.
,
Zuchner S.
,
Yamashita A.
,
Benomar A.
,
Goizet C.
,
Durr A.
,
Gleeson J.G.
,
Darios F.
,
Brice A.
,
Stevanin G.
more...
Am. J. Hum. Genet.91:1051-1064(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS SPG56 ARG-262; VAL-316; GLY-380 AND TRP-488