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Index > Protein center > Cyp3a1(Gene name) > Rat
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  • Cyp3a1 (Gene name),
  • Cytochrome P450 3A1 (Protein name ),  CP3A1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp3a1(Cyp3a-1);
    Protein name:
    Cytochrome P450 3A1;
    Alternative:
    CYPIIIA1;Cytochrome P450-PCN1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Function:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    504
    Sequence:
    50:
    MDLLSALTLE | TWVLLAVVLV | LLYGFGTRTH | GLFKKQGIPG | PKPLPFFGTV | 
    100:
    LNYYMGLWKF | DVECHKKYGK | IWGLFDGQMP | LFAITDTEMI | KNVLVKECFS | 
    150:
    VFTNRRDFGP | VGIMGKAVSV | AKDEEWKRYR | ALLSPTFTSG | RLKEMFPIIE | 
    200:
    QYGDILVKYL | KQEAETGKPV | TMKKVFGAYS | MDVITSTSFG | VNVDSLNNPK | 
    250:
    DPFVEKTKKL | LRFDFFDPLF | LSVVLFPFLT | PIYEMLNICM | FPKDSIEFFK | 
    300:
    KFVYRMKETR | LDSVQKHRVD | FLQLMMNAHN | DSKDKESHTA | LSDMEITAQS | 
    350:
    IIFIFAGYEP | TSSTLSFVLH | SLATHPDTQK | KLQEEIDRAL | PNKAPPTYDT | 
    400:
    VMEMEYLDMV | LNETLRLYPI | GNRLERVCKK | DVEINGVFMP | KGSVVMIPSY | 
    450:
    ALHRDPQHWP | EPEEFRPERF | SKENKGSIDP | YVYLPFGNGP | RNCIGMRFAL | 
    500:
    MNMKLALTKV | LQNFSFQPCK | ETQIPLKLSR | QGLLQPTKPI | ILKVVPRDEI | 
    504:
    ITGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 3A1
    Cat.:
    E2177r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Cytochrome P450 3A1
    Cat.:
    U2177r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Cytochrome P450 3A1
    Cat.:
    P2177Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Cytochrome P450 3A1
    Protein for Rat Cytochrome P450 3A1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family."
      Gonzalez F.J. , Nebert D.W. , Hardwick J.P. , Kasper C.B.
      J. Biol. Chem.260:7435-7441(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Cloning and characterization of a novel CYP3A1 allelic variant: analysis of CYP3A1 and CYP3A2 sex-hormone-dependent expression reveals that the CYP3A2 gene is regulated by testosterone."
      Ribeiro V. , Lechner M.C.
      Arch. Biochem. Biophys.293:147-152(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Liver.
    3. 3.
      "Purification and characterization of four catalytically active testosterone 6 beta-hydroxylase P-450s from rat liver microsomes: comparison of a novel form with three structurally and functionally related forms."
      Nagata K. , Gonzalez F.J. , Yamazoe Y. , Kato R.
      J. Biochem.107:718-725(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-26
    4. 4.
      "Regulation of two members of the steroid-inducible cytochrome P450 subfamily (3A) in rats."
      Cooper K.O. , Reik L.M. , Jayyosi Z. , Bandiera S. , Kelley M. , Ryan D.E. , Daniel R. , McCluskey S.A. , Levin W. , Thomas P.E.
      Arch. Biochem. Biophys.301:345-354(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-25
    5. 5.
      "Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes."
      Burger H.J. , Schuetz J.D. , Schuetz E.G. , Guzelian P.S.
      Proc. Natl. Acad. Sci. U.S.A.89:2145-2149(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-24
    6. 6.
      "Effect of dexamethasone and phenobarbital on run-on transcription rate and CYP3A mRNA concentration in rat liver: changes during development."
      Telhada M.B. , Pereira T.M. , Lechner M.C.
      Arch. Biochem. Biophys.298:715-725(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-24
      tissue: Liver.
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