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Index > Protein center > CYP4A6(Gene name) > Rabbit
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  • CYP4A6 (Gene name),
  • Cytochrome P450 4A6 (Protein name ),  CP4A6_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CYP4A6;
    Protein name:
    Cytochrome P450 4A6;
    Alternative:
    Cytochrome P450-KA-1;CYPIVA6;1.14.15.3;Lauric acid omega-hydroxylase);
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    The kidney P-450 system is rather specialized for the omega-hydroxylation of fatty acids. Both P450-KA1 and P450-KA2 catalyze the omega- and (omega-1)-hydroxylation of various fatty acids with no drug-metabolizing activity, and hydroxylate prostaglandin A1 and A2 solely at the omega-position.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    510
    Sequence:
    50:
    MSVSALNPTR | LPGSLSGLLQ | VAGLLGLLLL | LLKAAQLYLH | RQWLLRALQQ | 
    100:
    FPCPPFHWLL | GHSREFQNGH | ELQVMLKWVE | KFPSACPRWL | WGSRAHLLIY | 
    150:
    DPDYMKVILG | RSDPKAQGSY | RFLAPWIGYG | LLLLNGQTWF | QHRRMLTPAF | 
    200:
    HYDILKPYVG | LMADSVQIML | DKWEQLVSQD | SSLEVFQDIS | LMTLDTIMKC | 
    250:
    AFSHQGSVQL | DRNSQSYIQA | VGDLNNLFFS | RVRNVFHQSD | TIYRLSPEGR | 
    300:
    LSHRACQLAH | EHTDRVIQQR | KAQLQQEGEL | EKVRRKRRLD | FLDVLLFAKM | 
    350:
    ENGSSLSDQD | LRAEVDTFMF | EGHDTTASGI | SWIFYALATH | PEHQHRCREE | 
    400:
    IQGLLGDGAS | ITWEHLDQMP | YTTMCIKEAL | RLYPPVPGVG | RQLSSPVTFP | 
    450:
    DGRSLPKGVI | VTLSIYALHH | NPKVWPNPEV | FDPFPFAPGS | ARHSHAFLPF | 
    500:
    SGGPRNCIGK | QFAMNELKVA | VALTLVRFEL | LPDPKRVPDQ | KPRLVLKSSN | 
    510:
    GIHLRLRKLR | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Cytochrome P450 4A6
    CLIA Kit for Rabbit Cytochrome P450 4A6
    Polyclonal Antibody for Rabbit Cytochrome P450 4A6
    Monoclonal Antibody for Rabbit Cytochrome P450 4A6
    Protein for Rabbit Cytochrome P450 4A6

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and expression of three rabbit kidney cDNAs encoding lauric acid omega-hydroxylases."
      Johnson E.F. , Walker D.L. , Griffin K.J. , Clark J.E. , Okita R.T. , Meurhoff A.S. , Masters B.S.S.
      Biochemistry29:873-879(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    2. 2.
      "Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression."
      Yokotani N. , Bernhardt R. , Sogawa K. , Kusunose E. , Gotoh O. , Kusunose M. , Fujii-Kuriyama Y.
      J. Biol. Chem.264:21665-21669(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 5-24
      tissue: Kidney.
    3. 3.
      "Characterization of a rabbit gene encoding a clofibrate-inducible fatty acid omega-hydroxylase: CYP4A6."
      Muerhoff A.S. , Griffin K.J. , Johnson E.F.
      Arch. Biochem. Biophys.296:66-72(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Purification and characterization of two forms of cytochrome P-450 with omega-hydroxylase activities toward prostaglandin A and fatty acids from rabbit liver microsomes."
      Kikuta Y. , Kusunose E. , Okumoto T. , Kubota I. , Kusunose M.
      J. Biochem.107:280-286(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 5-24
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