CYP4F8 ELISA Kit for Human(Homo sapiens) | EIAab.comCYP4F8 ELISA Kit for Human(Homo sapiens)

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CYP4F8 (Gene name),

Cytochrome P450 4F8 (Protein name ), CP4F8_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CYP4F8;

Protein name:

Cytochrome P450 4F8;

Alternative:

CYPIVF8;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. Shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). Catalyzes hydrxylation of PGI2 and carbaprostacyclin.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass membrane protein Microsome membrane

Protein Attributes:

Sequence length:

520

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

520:

TPEIVLRAED | GLWLRVEPLG |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P98187

UniGene:

Hs.268554

Pfam:

PF00067

SMR:

P98187

MIM:

611545

KEGG:

hsa:11283

Uniprot:

P98187

FOR

ELISA Kit for Human Cytochrome P450 4F8

CLIA Kit for Human Cytochrome P450 4F8

Polyclonal Antibody for Human Cytochrome P450 4F8

Monoclonal Antibody for Human Cytochrome P450 4F8

Protein for Human Cytochrome P450 4F8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles."
Bylund J. , Finnstroem N. , Oliw E.H.
Biochem. Biophys. Res. Commun.261:169-174(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Seminal vesicle.
2.

"Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides."
Bylund J. , Hidestrand M. , Ingelman-Sundberg M. , Oliw E.H.
J. Biol. Chem.275:21844-21849(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
3.

"Expression of CYP4F8 (prostaglandin H 19-hydroxylase) in human epithelia and prominent induction in epidermis of psoriatic lesions."
Stark K. , Toermae H. , Cristea M. , Oliw E.H.
Arch. Biochem. Biophys.409:188-196(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8."
Stark K. , Wongsud B. , Burman R. , Oliw E.H.
Arch. Biochem. Biophys.441:174-181(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;VARIANT PHE-125;MUTAGENESIS OF GLY-328
5.

"On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens."
Stark K. , Bylund J. , Toermae H. , Sahlen G. , Oliw E.H.
Prostaglandins Other Lipid Mediat.75:47-64(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

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