Cyp7a1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCyp7a1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Cyp7a1(Gene name) > Rat

Cyp7a1 (Gene name),

Cholesterol 7-alpha-monooxygenase (Protein name ), CP7A1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cyp7a1(Cyp7);

Protein name:

Cholesterol 7-alpha-monooxygenase;

Alternative:

Cholesterol 7-alpha-hydroxylase;CYPVII;Cytochrome P450 7A1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.

Subcellular Location:

Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

503

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

503:

LKH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:25428

SMR:

P18125

Pfam:

PF00067

STRING:

10116.ENSRNOP00000012819

String:

P18125

UniGene:

Rn.10737

Uniprot:

P18125

FOR

ELISA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

E1053h

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96T

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ELISA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

E1053r

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96T

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ELISA Kit for Rat Cholesterol 7-alpha-monooxygenase

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ELISA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

E1053m

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Packing:

96T

ELISA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

E1053p

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96T

CLIA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

U1053m

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96T

CLIA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

U1053p

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Packing:

96T

CLIA Kit for Rat Cholesterol 7-alpha-monooxygenase

MSDS:

Please sign in first.

CLIA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

U1053r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

U1053h

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96T

Polyclonal Antibody for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-r

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40ug/0.2ml

Monoclonal Antibody for Rat Cholesterol 7-alpha-monooxygenase

Protein for Rat Cholesterol 7-alpha-monooxygenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA."
Li Y.C. , Wang D.P. , Chiang J.Y.L.
J. Biol. Chem.265:12012-12019(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;FUNCTION;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Liver.
2.

"Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis."
Jelinek D.F. , Andersson S. , Slaughter C.A. , Russell D.W.
J. Biol. Chem.265:8190-8197(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;CATALYTIC ACTIVITY;FUNCTION;INDUCTION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
3.

"Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expression."
Noshiro M. , Nishimoto M. , Morohashi K. , Okuda K.
FEBS Lett.257:97-100(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Rat liver cholesterol 7 alpha-hydroxylase. Pretranslational regulation for circadian rhythm."
Noshiro M. , Nishimoto M. , Okuda K.
J. Biol. Chem.265:10036-10041(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
5.

"Structural analysis of the gene encoding rat cholesterol alpha-hydroxylase, the key enzyme for bile acid biosynthesis."
Nishimoto M. , Gotoh O. , Okuda K. , Noshiro M.
J. Biol. Chem.266:6467-6471(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter."
Chiang J.Y. , Stroup D.
J. Biol. Chem.269:17502-17507(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-325
strain: Sprague-Dawley.
7.

"Structure of the rat gene encoding cholesterol 7 alpha-hydroxylase."
Jelinek D.F. , Russell D.W.
Biochemistry29:7781-7785(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-27
strain: Sprague-Dawley.
8.

"Cloning and 5'-flanking sequence of a rat cholesterol 7 alpha-hydroxylase gene."
Chiang J.Y. , Yang T.P. , Wang D.P.
Biochim. Biophys. Acta1132:337-339(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26
9.

"Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway."
Gupta S. , Stravitz R.T. , Dent P. , Hylemon P.B.
J. Biol. Chem.276:15816-15822(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION

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