Cplx1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCplx1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Cplx1(Gene name) > Rat

Cplx1 (Gene name),

Complexin-1 (Protein name ), CPLX1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cplx1;

Protein name:

Complexin-1;

Alternative:

Synaphin-2;Complexin I(CPX I);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds to the SNARE core complex containing SNAP25, VAMP2 and STX1A.

Function:

Positively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells.

Subcellular Location:

Cytoplasm cytosol Enriched at synaptic-releasing sites in mature neurons.

Protein Attributes:

Sequence length:

134

Sequence:

50:

100:

134:

IPPGCGDEPE | EEDESILDTV | IKYLPGPLQD | MFKK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.10133

SMR:

P63041

Pfam:

PF05835

String:

P63041

STRING:

10116.ENSRNOP00000058432

KEGG:

rno:64832

Uniprot:

P63041

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ELISA Kit for Rat Complexin-1

CLIA Kit for Rat Complexin-1

Polyclonal Antibody for Rat Complexin-1

Monoclonal Antibody for Rat Complexin-1

Protein for Rat Complexin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complexins: cytosolic proteins that regulate SNAP receptor function."
McMahon H.T. , Missler M. , Li C. , Suedhof T.C.
Cell83:111-119(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 19-49; 55-69 AND 74-96;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;SUBUNIT
tissue: Brain.
2.

"Distinct regional distribution in the brain of messenger RNAs for the two isoforms of synaphin associated with the docking/fusion complex."
Ishizuka T. , Saisu H. , Odani S. , Kumanishi T. , Abe T.
Neuroscience88:295-306(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

"Regulatory roles of complexins in neurotransmitter release from mature presynaptic nerve terminals."
Ono S. , Baux G. , Sekiguchi M. , Fossier P. , Morel N.F. , Nihonmatsu I. , Hirata K. , Awaji T. , Takahashi S. , Takahashi M.
Eur. J. Neurosci.10:2143-2152(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
5.

"Immunohistochemical distribution of the two isoforms of synaphin/complexin involved in neurotransmitter release: localization at the distinct central nervous system regions and synaptic types."
Yamada M. , Saisu H. , Ishizuka T. , Takahashi H. , Abe T.
Neuroscience93:7-18(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions."
Pabst S. , Hazzard J.W. , Antonin W. , Suedhof T.C. , Jahn R. , Rizo J. , Fasshauer D.
J. Biol. Chem.275:19808-19818(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
7.

"Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis."
Pabst S. , Margittai M. , Vainius D. , Langen R. , Jahn R. , Fasshauer D.
J. Biol. Chem.277:7838-7848(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
8.

"Structurally and functionally unique complexins at retinal ribbon synapses."
Reim K. , Wegmeyer H. , Brandstaetter J.H. , Xue M. , Rosenmund C. , Dresbach T. , Hofmann K. , Brose N.
J. Cell Biol.169:669-680(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
9.

"Three-dimensional structure of the complexin/SNARE complex."
Chen X. , Tomchick D.R. , Kovrigin E. , Arac D. , Machius M. , Suedhof T.C. , Rizo J.
Neuron33:397-409(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 26-83 IN COMPLEX WITH STX1A; SNAP25 AND VAMP2;STRUCTURE BY NMR

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