CPLX2 ELISA Kit for Human(Homo sapiens) | EIAab.comCPLX2 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CPLX2(Gene name) > Human

CPLX2 (Gene name),

Complexin-2 (Protein name ), CPLX2_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CPLX2;

Protein name:

Complexin-2;

Alternative:

Synaphin-1;Complexin II(CPX II);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to the SNARE core complex containing SNAP25, VAMP2 and STX1A.

Function:

Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis.

Subcellular Location:

Cytoplasm cytosol Enriched at synaptic-releasing sites in mature neurons.

Protein Attributes:

Sequence length:

134

Sequence:

50:

100:

134:

IPAGCGDEEE | EEEESILDTV | LKYLPGPLQD | MFKK

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q6PUV4

UniGene:

Hs.193235

MIM:

605033

Pfam:

PF05835

SMR:

Q6PUV4

STRING:

9606.ENSP00000352544

KEGG:

hsa:10814

Uniprot:

Q6PUV4

FOR

ELISA Kit for Human Complexin-2

CLIA Kit for Human Complexin-2

Polyclonal Antibody for Human Complexin-2

Monoclonal Antibody for Human Complexin-2

Protein for Human Complexin-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complexins: cytosolic proteins that regulate SNAP receptor function."
McMahon H.T. , Missler M. , Li C. , Suedhof T.C.
Cell83:111-119(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cerebellum.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

"Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity."
Raevskaya N.M. , Dergunova L.V. , Vladychenskaya I.P. , Stavchansky V.V. , Oborina M.V. , Poltaraus A.B. , Limborska S.A.
Gene359:127-137(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-114;TISSUE SPECIFICITY
tissue: Cerebellum.
5.

"Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia."
Harrison P.J. , Eastwood S.L.
Lancet352:1669-1673(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"Synaptic pathology in the anterior cingulate cortex in schizophrenia and mood disorders. A review and a Western blot study of synaptophysin, GAP-43 and the complexins."
Eastwood S.L. , Harrison P.J.
Brain Res. Bull.55:569-578(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
7.

"Cerebellar synaptic protein expression in schizophrenia."
Eastwood S.L. , Cotter D. , Harrison P.J.
Neuroscience105:219-229(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements."
DiProspero N.A. , Chen E.-Y. , Charles V. , Plomann M. , Kordower J.H. , Tagle D.A.
J. Neurocytol.33:517-533(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

Product Feedback Wall

* Email:
*Comments: