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Index > Protein center > Cpsf1(Gene name) > Mouse
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  • Cpsf1 (Gene name),
  • Cleavage and polyadenylation specificity factor subunit 1 (Protein name ),  CPSF1_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Cpsf1(Cpsf160);
    Protein name:
    Cleavage and polyadenylation specificity factor subunit 1;
    Alternative:
    Cleavage and polyadenylation specificity factor 160 kDa subunit(CPSF 160 kDa subunit);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with FIP1L1 and SRRM1. Interacts with TUT1; the interaction is direct and mediates the recruitment of the CPSF complex on the 3'UTR of selected pre-mRNAs (By similarity). Interacts with PAPD4/GLD2.
    Function:
    Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
    Subcellular Location:
    Nucleus nucleoplasm
    Protein Attributes:
    Sequence length:
    1441
    Sequence:
    50:
    MYAVYKQAHP | PTGLEFTMYC | NFFNNSERNL | VVAGTSQLYV | YRLNRDAEAL | 
    100:
    TKNDGSTEGK | AHREKLELVA | SFSFFGNVMS | MASVQLAGAK | RDALLLSFKD | 
    150:
    AKLSVVEYDP | GTHDLKTLSL | HYFEEPELRD | GFVQNVHTPR | VRVDPDGRCA | 
    200:
    AMLIYGTRLV | VLPFRRESLA | EEHEGLMGEG | QRSSFLPSYI | IDVRALDEKL | 
    250:
    LNIIDLQFLH | GYYEPTLLIL | FEPNQTWPGR | VAVRQDTCSI | VAISLNITQK | 
    300:
    VHPVIWSLTS | LPFDCTQALA | VPKPIGGVVI | FAVNSLLYLN | QSVPPYGVAL | 
    350:
    NSLTTGTTAF | PLRTQEGVRI | TLDCAQAAFI | SYDKMVISLK | GGEIYVLTLI | 
    400:
    TDGMRSVRAF | HFDKAAASVL | TTSMVTMEPG | YLFLGSRLGN | SLLLKYTEKL | 
    450:
    QEPPASSVRE | AADKEEPPSK | KKRVEPAVGW | TGGKTVPQDE | VDEIEVYGSE | 
    500:
    AQSGTQLATY | SFEVCDSMLN | IGPCANAAVG | EPAFLSEEFQ | NSPEPDLEIV | 
    550:
    VCSGYGKNGA | LSVLQKSIRP | QVVTTFELPG | CYDMWTVIAP | VRKEEEETPK | 
    600:
    AESTEQEPSA | PKAEEDGRRH | GFLILSREDS | TMILQTGQEI | MELDTSGFAT | 
    650:
    QGPTVFAGNI | GDNRYIVQVS | PLGIRLLEGV | NQLHFIPVDL | GAPIVQCAVA | 
    700:
    DPYVVIMSAE | GHVTMFLLKS | DSYGGRHHRL | ALHKPPLHHQ | SKVIALCLYR | 
    750:
    DVSGMFTTES | RLGGARDELG | GRSGSEAEGL | GSETSPTVDD | EEEMLYGDSS | 
    800:
    ALFSPSKEEA | RRSSQPPADR | DPAPFKADPT | HWCLLVRENG | TMEIYQLPDW | 
    850:
    RLVFLVKNFP | VGQRVLVDSS | FGQPTTQGEV | RKEEATRQGE | LPLVKEVLLV | 
    900:
    ALGSRQSRPY | LLVHVDQELL | IYEAFPHDSQ | LGQGNLKVRF | KKVPHNINFR | 
    950:
    EKKPKPSKKK | AEGCSTEEGS | GGRGRVARFR | YFEDIYGYSG | VFICGPSPHW | 
    1000:
    LLVTGRGALR | LHPMGIDGPI | DSFAPFHNVN | CPRGFLYFNR | QGELRISVLP | 
    1050:
    AYLSYDAPWP | VRKIPLRCTA | HYVAYHVESK | VYAVATSTNT | PCTRIPRMTG | 
    1100:
    EEKEFEAIER | DDRYIHPQQE | AFSIQLISPV | SWEAIPNARI | ELEEWEHVTC | 
    1150:
    MKTVSLRSEE | TVSGLKGYVA | AGTCLMQGEE | VTCRGRILIM | DVIEVVPEPG | 
    1200:
    QPLTKNKFKV | LYEKEQKGPV | TALCHCNGHL | VSAIGQKIFL | WSLRASELTG | 
    1250:
    MAFIDTQLYI | HQMISVKNFI | LAADVMKSIS | LLRYQEESKT | LSLVSRDAKP | 
    1300:
    LEVYSVDFMV | DNAQLGFLVS | DRDRNLMVYM | YLPEAKESFG | GMRLLRRADF | 
    1350:
    HVGAHVNTFW | RTPCRGAAEG | PSKKSVVWEN | KHITWFATLD | GGIGLLLPMQ | 
    1400:
    EKTYRRLLML | QNALTTMLPH | HAGLNPRAFR | MLHVDRRILQ | NAVRNVLDGE | 
    1441:
    LLNRYLYLST | MERSELAKKI | GTTPDIILDD | LLETDRVTAH | F
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1
    Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Overexpression of the CstF-64 and CPSF-160 polyadenylation protein messenger RNAs in mouse male germ cells."
      Dass B. , Attaya E.N. , Michelle Wallace A. , MacDonald C.C.
      Biol. Reprod.64:1722-1729(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells."
      Nakanishi T. , Kumagai S. , Kimura M. , Watanabe H. , Sakurai T. , Kimura M. , Kashiwabara S. , Baba T.
      Biochem. Biophys. Res. Commun.364:14-19(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PAPD4
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