Gene name:
Cpsf1 (Cpsf160) ;
Protein name:
Cleavage and polyadenylation specificity factor subunit 1 ;
Alternative:
Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with FIP1L1 and SRRM1. Interacts with TUT1; the interaction is direct and mediates the recruitment of the CPSF complex on the 3'UTR of selected pre-mRNAs (By similarity). Interacts with PAPD4/GLD2.
Function:
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Subcellular Location:
Nucleus
nucleoplasm
Protein Attributes:
50:
MYAVYKQAHP | PTGLEFTMYC | NFFNNSERNL | VVAGTSQLYV | YRLNRDAEAL |
100:
TKNDGSTEGK | AHREKLELVA | SFSFFGNVMS | MASVQLAGAK | RDALLLSFKD |
150:
AKLSVVEYDP | GTHDLKTLSL | HYFEEPELRD | GFVQNVHTPR | VRVDPDGRCA |
200:
AMLIYGTRLV | VLPFRRESLA | EEHEGLMGEG | QRSSFLPSYI | IDVRALDEKL |
250:
LNIIDLQFLH | GYYEPTLLIL | FEPNQTWPGR | VAVRQDTCSI | VAISLNITQK |
300:
VHPVIWSLTS | LPFDCTQALA | VPKPIGGVVI | FAVNSLLYLN | QSVPPYGVAL |
350:
NSLTTGTTAF | PLRTQEGVRI | TLDCAQAAFI | SYDKMVISLK | GGEIYVLTLI |
400:
TDGMRSVRAF | HFDKAAASVL | TTSMVTMEPG | YLFLGSRLGN | SLLLKYTEKL |
450:
QEPPASSVRE | AADKEEPPSK | KKRVEPAVGW | TGGKTVPQDE | VDEIEVYGSE |
500:
AQSGTQLATY | SFEVCDSMLN | IGPCANAAVG | EPAFLSEEFQ | NSPEPDLEIV |
550:
VCSGYGKNGA | LSVLQKSIRP | QVVTTFELPG | CYDMWTVIAP | VRKEEEETPK |
600:
AESTEQEPSA | PKAEEDGRRH | GFLILSREDS | TMILQTGQEI | MELDTSGFAT |
650:
QGPTVFAGNI | GDNRYIVQVS | PLGIRLLEGV | NQLHFIPVDL | GAPIVQCAVA |
700:
DPYVVIMSAE | GHVTMFLLKS | DSYGGRHHRL | ALHKPPLHHQ | SKVIALCLYR |
750:
DVSGMFTTES | RLGGARDELG | GRSGSEAEGL | GSETSPTVDD | EEEMLYGDSS |
800:
ALFSPSKEEA | RRSSQPPADR | DPAPFKADPT | HWCLLVRENG | TMEIYQLPDW |
850:
RLVFLVKNFP | VGQRVLVDSS | FGQPTTQGEV | RKEEATRQGE | LPLVKEVLLV |
900:
ALGSRQSRPY | LLVHVDQELL | IYEAFPHDSQ | LGQGNLKVRF | KKVPHNINFR |
950:
EKKPKPSKKK | AEGCSTEEGS | GGRGRVARFR | YFEDIYGYSG | VFICGPSPHW |
1000:
LLVTGRGALR | LHPMGIDGPI | DSFAPFHNVN | CPRGFLYFNR | QGELRISVLP |
1050:
AYLSYDAPWP | VRKIPLRCTA | HYVAYHVESK | VYAVATSTNT | PCTRIPRMTG |
1100:
EEKEFEAIER | DDRYIHPQQE | AFSIQLISPV | SWEAIPNARI | ELEEWEHVTC |
1150:
MKTVSLRSEE | TVSGLKGYVA | AGTCLMQGEE | VTCRGRILIM | DVIEVVPEPG |
1200:
QPLTKNKFKV | LYEKEQKGPV | TALCHCNGHL | VSAIGQKIFL | WSLRASELTG |
1250:
MAFIDTQLYI | HQMISVKNFI | LAADVMKSIS | LLRYQEESKT | LSLVSRDAKP |
1300:
LEVYSVDFMV | DNAQLGFLVS | DRDRNLMVYM | YLPEAKESFG | GMRLLRRADF |
1350:
HVGAHVNTFW | RTPCRGAAEG | PSKKSVVWEN | KHITWFATLD | GGIGLLLPMQ |
1400:
EKTYRRLLML | QNALTTMLPH | HAGLNPRAFR | MLHVDRRILQ | NAVRNVLDGE |
1441:
LLNRYLYLST | MERSELAKKI | GTTPDIILDD | LLETDRVTAH | F
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
ELISA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
CLIA Kit for Mouse Cleavage and polyadenylation specificity factor subunit 1
Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Polyclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Monoclonal Antibody for Mouse Cleavage and polyadenylation specificity factor subunit 1
Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1
Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1
Protein for Mouse Cleavage and polyadenylation specificity factor subunit 1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PAPD4