Orai1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comOrai1 ELISA Kit for Rat(Rattus norvegicus)

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Orai1 (Gene name),

Calcium release-activated calcium channel protein 1 (Protein name ), CRCM1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Orai1(Cracm1;Tmem142a);

Protein name:

Calcium release-activated calcium channel protein 1;

Alternative:

Transmembrane protein 142A;Protein orai-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with STIM1 and STIM2. Interacts with EFCAB4B/CRACR2A; the interaction is direct and takes place in absence of Ca(2+). Forms a complex with EFCAB4B/CRACR2A and STIM1 at low concentration of Ca(2+), the complex dissociates at elevated Ca(2+) concentrations.

Function:

Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

304

Sequence:

50:

100:

150:

200:

250:

300:

304:

THYA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:304496

String:

Q5M848

Pfam:

PF07856

UniGene:

Rn.3869

Uniprot:

Q5M848

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ELISA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

E15347r

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96T

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ELISA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

E15347h

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96T

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ELISA Kit for Rat Calcium release-activated calcium channel protein 1

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E15347m

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ELISA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

E15347c

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96T

CLIA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

U15347h

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96T

CLIA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

U15347r

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MSDS:

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Packing:

96T

CLIA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

U15347m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Calcium release-activated calcium channel protein 1

Cat.:

U15347c

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Packing:

96T

Polyclonal Antibody for Rat Calcium release-activated calcium channel protein 1

Cat.:

P15347Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Calcium release-activated calcium channel protein 1

Cat.:

P15347Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Calcium release-activated calcium channel protein 1

Cat.:

P15347Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Calcium release-activated calcium channel protein 1

Protein for Rat Calcium release-activated calcium channel protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
2.

"Crystal structure of calmodulin binding domain of orai1 in complex with Ca2+ calmodulin displays a unique binding mode."
Liu Y. , Zheng X. , Mueller G.A. , Sobhany M. , DeRose E.F. , Zhang Y. , London R.E. , Birnbaumer L.
J. Biol. Chem.287:43030-43041(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ORAI1

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