Chrdl1 ELISA Kit for Mouse(Mus musculus) | EIAab.comChrdl1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Chrdl1(Gene name) > Mouse

Chrdl1 (Gene name),

Chordin-like protein 1 (Protein name ), CRDL1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Chrdl1(Ng1;Nrln1);

Protein name:

Chordin-like protein 1;

Alternative:

Neurogenesin-1;Neuralin-1;Ventroptin;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation (By similarity). Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

447

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

447:

RTTLNQWKLF | TEGEAQLSQM | CSSQVCRTEL | EDLVQVLYLG | RPEKDHC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q920C1

KEGG:

mmu:83453

Pfam:

PF00093

SMR:

Q920C1

UniGene:

Mm.157697

Uniprot:

Q920C1

FOR

ELISA Kit for Mouse Chordin-like protein 1

CLIA Kit for Mouse Chordin-like protein 1

Polyclonal Antibody for Mouse Chordin-like protein 1

Monoclonal Antibody for Mouse Chordin-like protein 1

Protein for Mouse Chordin-like protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Ventroptin: a BMP-4 antagonist expressed in a double-gradient pattern in the retina."
Sakuta H. , Suzuki R. , Takahashi H. , Kato A. , Shintani T. , Iemura S. , Yamamoto T.S. , Ueno N. , Noda M.
Science293:111-115(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA AND BETA)
strain: C57BL/6J.
2.

"Neuralin-1 is a novel chordin-related molecule expressed in the mouse neural plate."
Coffinier C.C. , Tran U. , Larrain J. , De Robertis E.M.
Mech. Dev.100:119-122(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA)
3.

"Neurogenesin-1 differentially inhibits the osteoblastic differentiation by bone morphogenetic proteins in C2C12 cells."
Chandra A. , Itakura T. , Yang Z. , Tamakoshi T. , Xue X. , Wang B. , Ueki T. , Sato K. , Uezato T. , Miura N.
Biochem. Biophys. Res. Commun.344:786-791(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;GLYCOSYLATION;DEVELOPMENTAL STAGE

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