Crem ELISA Kit for Mouse(Mus musculus) | EIAab.comCrem ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Crem(Gene name) > Mouse

Crem (Gene name),

cAMP-responsive element modulator (Protein name ), CREM_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Crem;

Protein name:

cAMP-responsive element modulator;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds DNA as a dimer (By similarity). Interacts with CDC34 (By similarity). Interacts with FHL5. Isoform 1 forms a heterodimer with CREB3L4.

Function:

Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform 2, isoform 3 and isoform 4 are repressors, while isoform 1 is an activator. Plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform 1 (activator) to CRE is increased by CREB3L4. The CREM isoform 1-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

357

Sequence:

50:

100:

150:

200:

250:

300:

350:

357:

ICSPKTD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00170

SMR:

P27699

KEGG:

mmu:12916

UniGene:

Mm.5244

String:

P27699

Uniprot:

P27699

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ELISA Kit for Mouse cAMP-responsive element modulator

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E15147h

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ELISA Kit for Mouse cAMP-responsive element modulator

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E15147m

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ELISA Kit for Mouse cAMP-responsive element modulator

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E15147r

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ELISA Kit for Mouse cAMP-responsive element modulator

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E15147d

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ELISA Kit for Mouse cAMP-responsive element modulator

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E15147b

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96T

CLIA Kit for Mouse cAMP-responsive element modulator

Cat.:

U15147h

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96T

CLIA Kit for Mouse cAMP-responsive element modulator

Cat.:

U15147r

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96T

CLIA Kit for Mouse cAMP-responsive element modulator

Cat.:

U15147m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse cAMP-responsive element modulator

Cat.:

U15147b

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96T

CLIA Kit for Mouse cAMP-responsive element modulator

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U15147d

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96T

Polyclonal Antibody for Mouse cAMP-responsive element modulator

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P15147Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse cAMP-responsive element modulator

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P15147Rb-h

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Polyclonal Antibody for Mouse cAMP-responsive element modulator

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P15147Rb-r

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Monoclonal Antibody for Mouse cAMP-responsive element modulator

Protein for Mouse cAMP-responsive element modulator

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor."
Molina C.A. , Foulkes N.S. , Lalli E. , Sassone-Corsi P.
Cell75:875-886(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 11);ALTERNATIVE PROMOTER USAGE;SUBCELLULAR LOCATION;INDUCTION
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription."
Foulkes N.S. , Borrelli E. , Sassone-Corsi P.
Cell64:739-749(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 7-357 (ISOFORMS 2; 3 AND 4)
4.

"Identification of novel cAMP responsive element modulator (CREM) isoforms expressed by osteoblasts."
Liu F. , Huang Y.-F. , Kream B.E.
Calcif. Tissue Int.77:91-95(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-357 (ISOFORMS 5; 6; 7; 8; 9 AND 10)
tissue: Osteoblast.
5.

"Developmental switch of CREM function during spermatogenesis: from antagonist to activator."
Foulkes N.S. , Mellstroem B. , Benusiglio E. , Sassone-Corsi P.
Nature355:80-84(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-357 (ISOFORM 1)
6.

"CBP-independent activation of CREM and CREB by the LIM-only protein ACT."
Fimia G.M. , De Cesare D. , Sassone-Corsi P.
Nature398:165-169(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FHL5
7.

"Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation."
Nagamori I. , Yomogida K. , Adams P.D. , Sassone-Corsi P. , Nojima H.
J. Biol. Chem.281:15073-15081(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CREB3L4
8.

"Inducible cAMP early repressor regulates the Period 1 gene of the hepatic and adrenal clocks."
Zmrzljak U.P. , Korencic A. , Kosir R. , Golicnik M. , Sassone-Corsi P. , Rozman D.
J. Biol. Chem.288:10318-10327(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION (ISOFORM 11);ALTERNATIVE PROMOTER USAGE;SUBCELLULAR LOCATION;INDUCTION

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