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Index > Protein center > Crhr1(Gene name) > Rat
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  • Crhr1 (Gene name),
  • Corticotropin-releasing factor receptor 1 (Protein name ),  CRFR1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Crhr1(Crhr);
    Protein name:
    Corticotropin-releasing factor receptor 1(CRF-R-1;CRF-R1;CRFR-1);
    Alternative:
    Corticotropin-releasing hormone receptor 1(CRH-R-1;CRH-R1);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts (via N-terminal extracellular domain) with CRF and UCN.
    Function:
    Receptor for corticotropin releasing factor (CRH). Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    415
    Sequence:
    50:
    MGRRPQLRLV | KALLLLGLNP | VSTSLQDQRC | ENLSLTSNVS | GLQCNASVDL | 
    100:
    IGTCWPRSPA | GQLVVRPCPA | FFYGVRYNTT | NNGYRECLAN | GSWAARVNYS | 
    150:
    ECQEILNEEK | KSKVHYHVAV | IINYLGHCIS | LVALLVAFVL | FLRLRSIRCL | 
    200:
    RNIIHWNLIS | AFILRNATWF | VVQLTVSPEV | HQSNVAWCRL | VTAAYNYFHV | 
    250:
    TNFFWMFGEG | CYLHTAIVLT | YSTDRLRKWM | FVCIGWGVPF | PIIVAWAIGK | 
    300:
    LHYDNEKCWF | GKRPGVYTDY | IYQGPMILVL | LINFIFLFNI | VRILMTKLRA | 
    350:
    STTSETIQYR | KAVKATLVLL | PLLGITYMLF | FVNPGEDEVS | RVVFIYFNSF | 
    400:
    LESFQGFFVS | VFYCFLNSEV | RSAIRKRWRR | WQDKHSIRAR | VARAMSIPTS | 
    415:
    PTRVSFHSIK | QSTAV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat CRF-R-1
    Cat.:
    E1168r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat CRF-R-1
    Cat.:
    E1168h
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    96T
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    ELISA Kit for Rat CRF-R-1
    Cat.:
    E1168c
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    96T
    ELISA Kit for Rat CRF-R-1
    Cat.:
    E1168m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat CRF-R-1
    Cat.:
    U1168c
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    Packing:
    96T
    CLIA Kit for Rat CRF-R-1
    Cat.:
    U1168m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CRF-R-1
    Cat.:
    U1168h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat CRF-R-1
    Cat.:
    U1168r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    Polyclonal Antibody for Rat CRF-R-1
    Cat.:
    P1168Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CRF-R-1
    Cat.:
    P1168Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CRF-R-1
    Cat.:
    P1168Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CRF-R-1
    Monoclonal Antibody for Rat CRF-R-1
    Monoclonal Antibody for Rat CRF-R-1
    Monoclonal Antibody for Rat CRF-R-1
    Monoclonal Antibody for Rat CRF-R-1
    Protein for Rat CRF-R-1
    Protein for Rat CRF-R-1
    Protein for Rat CRF-R-1
    Protein for Rat CRF-R-1

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    References
    1. 1.
      "Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor."
      Perrin M.H. , Donaldson C.J. , Chen R. , Lewis K.A. , Vale W.W.
      Endocrinology133:3058-3061(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
      strain: Sprague-Dawley.
      tissue: Brain.
    2. 2.
      "Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain."
      Chang C.P. , Pearse R.V. II , O'Connell S. , Rosenfeld M.G.
      Neuron11:1187-1195(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Cerebellum.
    3. 3.
      "The genomic structure of the rat corticotropin releasing factor receptor. A member of the class II G protein-coupled receptors."
      Tsai-Morris C.-H. , Buczko E. , Geng Y. , Gamboa-Pinto A. , Dufau M.L.
      J. Biol. Chem.271:14519-14525(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Testis.
    4. 4.
      "Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1."
      Hofmann B.A. , Sydow S. , Jahn O. , van Werven L. , Liepold T. , Eckart K. , Spiess J.
      Protein Sci.10:2050-2062(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISULFIDE BONDS;GLYCOSYLATION AT ASN-38; ASN-45; ASN-78; ASN-90 AND ASN-98
    5. 5.
      "Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines."
      Akama K.T. , Thompson L.I. , Milner T.A. , McEwen B.S.
      J. Biol. Chem.288:6438-6450(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
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