Protein name:
Cone-rod homeobox protein ;
Alternative:
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Interacts with SCA7 (By similarity). Interacts with RAX2. Interacts (via the homeobox) with NRL (via the leucine-zipper domain).
Function:
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MMAYMNPGPH | YSVNALALSG | PSVDLMHQAV | SYPSAPRKQR | RERTTFTRSQ |
100:
LEELEALFAK | TQYPDVYARE | EVALKINLPE | SRVQVWFKNR | RAKCRQQRQQ |
150:
QKEQPQPPGA | QTKARPAKRK | AGMSPRSSSD | VCPDPLGISD | SYSPPLLGPS |
200:
GSPTTAVATV | SIWSPASESP | LPEAQRGGLV | ASGPPLTSTP | YAMTYAPASA |
250:
FCSSPSAYGS | PSSYFSGLDP | YLSPMVPQLG | GPALSPLSGP | SVGPSLAQSP |
299:
TSLSGQSYGT | YSPVDSLEFK | DPTGTWKFTY | NPMDPLDYKD | QSAWKFQIL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Dog
Mouse
Human
ELISA Kit for Dog Cone-rod homeobox protein
ELISA Kit for Dog Cone-rod homeobox protein
ELISA Kit for Dog Cone-rod homeobox protein
ELISA Kit for Dog Cone-rod homeobox protein
CLIA Kit for Dog Cone-rod homeobox protein
CLIA Kit for Dog Cone-rod homeobox protein
CLIA Kit for Dog Cone-rod homeobox protein
CLIA Kit for Dog Cone-rod homeobox protein
Polyclonal Antibody for Dog Cone-rod homeobox protein
Polyclonal Antibody for Dog Cone-rod homeobox protein
Polyclonal Antibody for Dog Cone-rod homeobox protein
Polyclonal Antibody for Dog Cone-rod homeobox protein
Monoclonal Antibody for Dog Cone-rod homeobox protein
Monoclonal Antibody for Dog Cone-rod homeobox protein
Monoclonal Antibody for Dog Cone-rod homeobox protein
Monoclonal Antibody for Dog Cone-rod homeobox protein
Protein for Dog Cone-rod homeobox protein
Protein for Dog Cone-rod homeobox protein
Protein for Dog Cone-rod homeobox protein
Protein for Dog Cone-rod homeobox protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and characterization of the canine photoreceptor specific cone-rod homeobox (CRX) gene and evaluation as a candidate for early onset photoreceptor diseases in the dog."
Akhmedov N.B.
,
Baldwin V.J.
,
Zangerl B.
,
Kijas J.W.
,
Hunter L.
,
Minoofar K.D.
,
Mellersh C.
,
Ostrander E.A.
,
Acland G.M.
,
Farber D.B.
,
Aguirre G.D.
Mol. Vis.8:79-84(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"Characterization of the canine CRX gene."
Dekomien G.
,
Epplen J.T.
Submitted (2002-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]