CSF1R ELISA Kit for Human(Homo sapiens) | EIAab.comCSF1R ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CSF1R(Gene name) > Human

CSF1R (Gene name),

Macrophage colony-stimulating factor 1 receptor (Protein name ), CSF1R_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

CSF1R(FMS);

Protein name:

Macrophage colony-stimulating factor 1 receptor(CSF-1-R);

Alternative:

Proto-oncogene c-Fms;2.7.10.1;Proto-oncogene c-Fms(CSF-1-R);

CD:

CD115;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with INPPL1/SHIP2 and THOC5.

Function:

Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

972

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

972:

LTCCEQGDIA | QPLLQPNNYQ | FC

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

KEGG:

hsa:1436

SMR:

P07333

MIM:

164770

STRING:

9606.ENSP00000286301

UniGene:

Hs.586219

String:

P07333

Pfam:

PF00047

Uniprot:

P07333

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ELISA Kit for Human CSF-1-R

Cat.:

E1594h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human CSF-1-R

Cat.:

E1594m

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MSDS:

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Packing:

96T

ELISA Kit for Human CSF-1-R

Cat.:

E1594r

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Packing:

96T

CLIA Kit for Human CSF-1-R

Cat.:

U1594h

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MSDS:

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Packing:

96T

CLIA Kit for Human CSF-1-R

Cat.:

U1594m

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MSDS:

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Packing:

96T

CLIA Kit for Human CSF-1-R

Cat.:

U1594r

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96T

Polyclonal Antibody for Human CSF-1-R

Cat.:

P1594Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CSF-1-R

Cat.:

P1594Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CSF-1-R

Cat.:

P1594Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human CSF-1-R

Protein for Human CSF-1-R

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Nucleotide sequence and structural organization of the human FMS proto-oncogene."
Hampe A. , Shamoon B.M. , Gobet M. , Sherr C.J. , Galibert F.
Oncogene Res.4:9-17(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus."
Coussens L. , van Beveren C. , Smith D. , Chen E. , Mitchell R.L. , Isacke C.M. , Verma I.M. , Ullrich A.
Nature320:277-280(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes."
Andre C. , Hampe A. , Lachaume P. , Martin E. , Wang X.P. , Manus V. , Hu W.X. , Galibert F.
Genomics39:216-226(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
4.

"Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis."
Jin P. , Zhang J. , Sumariwalla P.F. , Ni I. , Jorgensen B. , Crawford D. , Phillips S. , Feldmann M. , Shepard H.M. , Paleolog E.M.
Arthritis Res. Ther.10:R73-R73(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
5.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
8.

"Differential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytes."
Visvader J. , Verma I.M.
Mol. Cell. Biol.9:1336-1341(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16
9.

"The amino-terminal domain of the v-fms oncogene product includes a functional signal peptide that directs synthesis of a transforming glycoprotein in the absence of feline leukemia virus gag sequences."
Wheeler E.F. , Roussel M.F. , Hampe A. , Walker M.H. , Fried V.A. , Look A.T. , Rettenmier C.W. , Sherr C.J.
J. Virol.59:224-233(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16
10.

"Expression of a novel exon in the 5' UTR of human c-fms transcripts."
Flick M.B. , Sapi E. , Kacinski B.M.
Submitted (1996-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16
tissue: Placenta.
11.

"Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q- syndrome."
Nienhuis A.W. , Bunn H.F. , Turner P.H. , Gopal T.V. , Nash W.G. , O'Brien S.J. , Sherr C.J.
Cell42:421-428(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 244-295
12.

"'Replacement' of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential."
Browning P.J. , Bunn H.F. , Cline A. , Shuman M. , Nienhuis A.W.
Proc. Natl. Acad. Sci. U.S.A.83:7800-7804(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 874-972 (ISOFORM 1)
13.

"Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential."
Bourette R.P. , Mouchiroud G. , Ouazana R. , Morle F. , Godet J. , Blanchet J.P.
Blood81:2511-2520(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELL PROLIFERATION
14.

"Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor."
Courtneidge S.A. , Dhand R. , Pilat D. , Twamley G.M. , Waterfield M.D. , Roussel M.F.
EMBO J.12:943-950(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRC; FYN AND YES1;MUTAGENESIS OF TYR-809
15.

"Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids."
Sapi E. , Flick M.B. , Gilmore-Hebert M. , Rodov S. , Kacinski B.M.
Oncogene10:529-542(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY GLUCOCORTICOIDS
16.

"Cell specific transformation by c-fms activating loop mutations is attributable to constitutive receptor degradation."
Morley G.M. , Uden M. , Gullick W.J. , Dibb N.J.
Oncogene18:3076-3084(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TYR-708 AND ASP-802
17.

"The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity."
Baran C.P. , Tridandapani S. , Helgason C.D. , Humphries R.K. , Krystal G. , Marsh C.B.
J. Biol. Chem.278:38628-38636(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELLULAR SIGNALING; PHOSPHORYLATION OF INPP5D AND ACTIVATION OF AKT1
18.

"Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture."
Wrobel C.N. , Debnath J. , Lin E. , Beausoleil S. , Roussel M.F. , Brugge J.S.
J. Cell Biol.165:263-273(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF CELL PROLIFERATION; CELL ADHESION; CELL SHAPE AND INTEGRITY OF CELL JUNCTIONS;MUTAGENESIS OF LEU-301 AND TYR-969;ROLE IN DISEASE
19.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-302 AND ASN-353
tissue: Plasma.
20.

"Inhibition of phosphorylation of the colony-stimulating factor-1 receptor (c-Fms) tyrosine kinase in transfected cells by ABT-869 and other tyrosine kinase inhibitors."
Guo J. , Marcotte P.A. , McCall J.O. , Dai Y. , Pease L.J. , Michaelides M.R. , Davidsen S.K. , Glaser K.B.
Mol. Cancer Ther.5:1007-1013(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS CSF1 RECEPTOR;CATALYTIC ACTIVITY;AUTOPHOSPHORYLATION;ROLE IN DISEASE;ENZYME REGULATION
21.

"A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model."
Ohno H. , Kubo K. , Murooka H. , Kobayashi Y. , Nishitoba T. , Shibuya M. , Yoneda T. , Isoe T.
Mol. Cancer Ther.5:2634-2643(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELL PROLIFERATION;CATALYTIC ACTIVITY;AUTOPHOSPHORYLATION;ROLE IN DISEASE;ENZYME REGULATION
22.

"FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance."
Taylor J.R. , Brownlow N. , Domin J. , Dibb N.J.
Oncogene25:147-151(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF CELL PROLIFERATION AND CELL SHAPE;CATALYTIC ACTIVITY;UBIQUITINATION;ENZYME REGULATION;MUTAGENESIS OF ASP-802
23.

"Discovery of a cytokine and its receptor by functional screening of the extracellular proteome."
Lin H. , Lee E. , Hestir K. , Leo C. , Huang M. , Bosch E. , Halenbeck R. , Wu G. , Zhou A. , Behrens D. , Hollenbaugh D. , Linnemann T. , Qin M. , Wong J. , Chu K. , Doberstein S.K. , Williams L.T.
Science320:807-811(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS IL34 RECEPTOR
24.

"Imatinib mesylate suppresses bone metastases of breast cancer by inhibiting osteoclasts through the blockade of c-Fms signals."
Hiraga T. , Nakamura H.
Int. J. Cancer124:215-222(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN DISEASE;ENZYME REGULATION
25.

"Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor."
Patsialou A. , Wyckoff J. , Wang Y. , Goswami S. , Stanley E.R. , Condeelis J.S.
Cancer Res.69:9498-9506(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN DISEASE
26.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-699 AND SER-713;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
27.

"Colony stimulating factor-1 receptor as a target for small molecule inhibitors."
Mashkani B. , Griffith R. , Ashman L.K.
Bioorg. Med. Chem.18:1789-1797(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: AUTOPHOSPHORYLATION;ENZYME REGULATION
28.

"IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation."
Chihara T. , Suzu S. , Hassan R. , Chutiwitoonchai N. , Hiyoshi M. , Motoyoshi K. , Kimura F. , Okada S.
Cell Death Differ.17:1917-1927(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS RECEPTOR FOR IL34 AND CSF1;PHOSPHORYLATION AT TYR-546; TYR-699; TYR-708; TYR-723 AND TYR-809;AUTOPHOSPHORYLATION;ENZYME REGULATION;INTERACTION WITH IL34 AND CSF1
29.

"Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood."
Eda H. , Zhang J. , Keith R.H. , Michener M. , Beidler D.R. , Monahan J.B.
Cytokine52:215-220(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN RELEASE OF PROINFLAMMATORY CHEMOKINES
30.

"Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells."
Wei S. , Nandi S. , Chitu V. , Yeung Y.G. , Yu W. , Huang M. , Williams L.T. , Lin H. , Stanley E.R.
J. Leukoc. Biol.88:495-505(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS IL34 AND CSF1 RECEPTOR; ACTIVATION OF MAPK1/ERK2; MAPK3/ERK1; PHOSPHORYLATION AT TYR-723;AUTOPHOSPHORYLATION
31.

"CSF-1 regulation of the wandering macrophage: complexity in action."
Pixley F.J. , Stanley E.R.
Trends Cell Biol.14:628-638(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION; SIGNALING PATHWAYS AND PHOSPHORYLATION
32.

"Colony-stimulating factor-1 in immunity and inflammation."
Chitu V. , Stanley E.R.
Curr. Opin. Immunol.18:39-48(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION IN IMMUNITY AND INFLAMMATION;ROLE IN DISEASE
33.

"Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies."
Douglass T.G. , Driggers L. , Zhang J.G. , Hoa N. , Delgado C. , Williams C.C. , Dan Q. , Sanchez R. , Jeffes E.W. , Wepsic H.T. , Myers M.P. , Koths K. , Jadus M.R.
Int. Immunopharmacol.8:1354-1376(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION; SIGNALING PATHWAYS AND PHOSPHORYLATION
34.

"Blood monocytes: development, heterogeneity, and relationship with dendritic cells."
Auffray C. , Sieweke M.H. , Geissmann F.
Annu. Rev. Immunol.27:669-692(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
35.

"Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors."
Schubert C. , Schalk-Hihi C. , Struble G.T. , Ma H.C. , Petrounia I.P. , Brandt B. , Deckman I.C. , Patch R.J. , Player M.R. , Spurlino J.C. , Springer B.A.
J. Biol. Chem.282:4094-4101(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 538-922 IN COMPLEXES WITH ARYLAMIDE AND QUINOLONE INHIBITORS;DOMAIN
36.

"The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain."
Walter M. , Lucet I.S. , Patel O. , Broughton S.E. , Bamert R. , Williams N.K. , Fantino E. , Wilks A.F. , Rossjohn J.
J. Mol. Biol.367:839-847(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 543-918 IN AUTOINHIBITED CONFORMATION;DOMAIN
37.

"Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors."
Huang H. , Hutta D.A. , Hu H. , DesJarlais R.L. , Schubert C. , Petrounia I.P. , Chaikin M.A. , Manthey C.L. , Player M.R.
Bioorg. Med. Chem. Lett.18:2355-2361(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.02 ANGSTROMS) OF 538-922 IN COMPLEX WITH PYRIMIDINOPYRIDONE INHIBITOR;CATALYTIC ACTIVITY
38.

"Pyrido[2,3-d]pyrimidin-5-ones: a novel class of antiinflammatory macrophage colony-stimulating factor-1 receptor inhibitors."
Huang H. , Hutta D.A. , Rinker J.M. , Hu H. , Parsons W.H. , Schubert C. , DesJarlais R.L. , Crysler C.S. , Chaikin M.A. , Donatelli R.R. , Chen Y. , Cheng D. , Zhou Z. , Yurkow E. , Manthey C.L. , Player M.R.
J. Med. Chem.52:1081-1099(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 538-922 IN COMPLEX WITH INHIBITOR;CATALYTIC ACTIVITY;FUNCTION IN INFLAMMATION AND DISEASE
39.

"Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode."
Meyers M.J. , Pelc M. , Kamtekar S. , Day J. , Poda G.I. , Hall M.K. , Michener M.L. , Reitz B.A. , Mathis K.J. , Pierce B.S. , Parikh M.D. , Mischke D.A. , Long S.A. , Parlow J.J. , Anderson D.R. , Thorarensen A.
Bioorg. Med. Chem. Lett.20:1543-1547(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 538-922 IN COMPLEXES WITH INHIBITORS;CATALYTIC ACTIVITY;ENZYME REGULATION
40.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLY-32; ARG-362; SER-413; VAL-536; HIS-693; ASP-920 AND GLN-921
41.

"Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids."
Rademakers R. , Baker M. , Nicholson A.M. , Rutherford N.J. , Finch N. , Soto-Ortolaza A. , Lash J. , Wider C. , Wojtas A. , DeJesus-Hernandez M. , Adamson J. , Kouri N. , Sundal C. , Shuster E.A. , Aasly J. , MacKenzie J. , Roeber S. , Kretzschmar H.A. , more...
Nat. Genet.44:200-205(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HDLS 774-CYS--ASN-814 DEL; 585-GLY--LYS-619 DELINS ALA; GLU-589; LYS-633; THR-766; PRO-770; ASN-775; THR-794; TYR-837; SER-849; PHE-849 DEL; PRO-868; THR-875 AND THR-878;VARIANTS HIS-710; ARG-747 AND ASP-920;CHARACTERIZATION OF VARIANTS HDLS LYS-633; THR-766 AND THR-875

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