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Index > Protein center > Csf1(Gene name) > Rat
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  • Csf1 (Gene name),
  • Macrophage colony-stimulating factor 1 (Protein name ),  CSF1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Csf1(Csfm);
    Protein name:
    Macrophage colony-stimulating factor 1(CSF-1;MCSF);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer or heterodimer; disulfide-linked.
    Function:
    Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
    Subcellular Location:
    Processed macrophage colony-stimulating factor 1 Secreted extracellular space
    Protein Attributes:
    Sequence length:
    566
    Sequence:
    50:
    MTARGAAGRC | PSSTWMGSRL | LLVCLLVSRS | VAEVSEHCSH | MIGNGHLQIL | 
    100:
    QQLIDSQMET | ACLIEYKFVD | QEQLDDPVCY | LKKAFVLVQV | IIEETMRFKD | 
    150:
    NTPNANATER | LQELSMKLNS | CFIKDYKEQN | EACVQTYKES | PLRLLEKIKN | 
    200:
    FFNETKNFLE | KDWNIFSKNC | NDSFAKCSSR | DVVTKPDCNC | LYPKATPSSD | 
    250:
    LASASPHQPP | APSMAPLADL | AWDDSQRTEG | SSLLPSDLPL | RIEDPGSAKQ | 
    300:
    RPPRSTCQTL | ESTEQPNHED | PQPHPSAGAP | IPGVEDIIES | SMGTNWVLEE | 
    350:
    ASGEASEGFL | TQERKFSPSN | PVGGSIQAET | DRPWARSASS | PFPKLTEDQQ | 
    400:
    PTNITDTPLT | EVNPMRPTGQ | TLNNTPEKTD | GSSTLREDQQ | EPRSPHFATL | 
    450:
    NPQRVGNSAT | PYAKLLPPKS | HSWGIVLPLG | ELEGKKSTRD | RRSPAELKGG | 
    500:
    PASEGAARPV | AQSTRDRRSP | AELKGGPASE | GAARPVARFN | SIPLTDTGSS | 
    550:
    IQDPQTSAFV | FWVLGIILVL | LAVGGLLFYS | WKRRSHRDPR | TLDSSVGRPE | 
    566:
    GSSLAQDEDR | QVELPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat CSF-1
    Cat.:
    E0090h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat CSF-1
    Cat.:
    E0090m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat CSF-1
    Cat.:
    E0090r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat CSF-1
    Cat.:
    U0090r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat CSF-1
    Cat.:
    U0090h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CSF-1
    Cat.:
    U0090m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat CSF-1
    Cat.:
    P0090Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CSF-1
    Cat.:
    P0090Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CSF-1
    Cat.:
    P0090Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat CSF-1
    Monoclonal Antibody for Rat CSF-1
    Monoclonal Antibody for Rat CSF-1
    Protein for Rat CSF-1
    Protein for Rat CSF-1
    Protein for Rat CSF-1

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    References
    1. 1.
      "Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat."
      Dobbins D.E. , Sood R. , Hashiramoto A. , Hansen C.T. , Wilder R.L. , Remmers E.F.
      Biochem. Biophys. Res. Commun.294:1114-1120(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DISEASE
      strain: Brown Norway/SsN.
      strain: Lewis/N.
    2. 2.
      "The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification."
      Van Wesenbeeck L. , Odgren P.R. , MacKay C.A. , D'Angelo M. , Safadi F.F. , Popoff S.N. , Van Hul W. , Marks S.C. Jr.
      Proc. Natl. Acad. Sci. U.S.A.99:14303-14308(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DISEASE
      strain: Fischer 344.
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