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Index > Protein center > CSF3(Gene name) > Human
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  • CSF3 (Gene name),
  • Granulocyte colony-stimulating factor (Protein name ),  CSF3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CSF3(C17orf33;GCSF);
    Protein name:
    Granulocyte colony-stimulating factor(G-CSF);
    Alternative:
    Pluripoietin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    207
    Sequence:
    50:
    MAGPATQSPM | KLMALQLLLW | HSALWTVQEA | TPLGPASSLP | QSFLLKCLEQ | 
    100:
    VRKIQGDGAA | LQEKLVSECA | TYKLCHPEEL | VLLGHSLGIP | WAPLSSCPSQ | 
    150:
    ALQLAGCLSQ | LHSGLFLYQG | LLQALEGISP | ELGPTLDTLQ | LDVADFATTI | 
    200:
    WQQMEELGMA | PALQPTQGAM | PAFASAFQRR | AGGVLVASHL | QSFLEVSYRV | 
    207:
    LRHLAQP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human G-CSF
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    E0042h
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    ELISA Kit for Human G-CSF
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    E0042m
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    ELISA Kit for Human G-CSF
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    E0042b
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    ELISA Kit for Human G-CSF
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    E0042d
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    ELISA Kit for Human G-CSF
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    E0042p
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    CLIA Kit for Human G-CSF
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    U0042m
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    96T
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    CLIA Kit for Human G-CSF
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    U0042h
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    Please sign in first.
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    Please sign in first.
    Packing:
    96T
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    CLIA Kit for Human G-CSF
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    U0042b
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    Packing:
    96T
    CLIA Kit for Human G-CSF
    Cat.:
    U0042d
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    96T
    CLIA Kit for Human G-CSF
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    U0042p
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human G-CSF
    Cat.:
    P0042Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human G-CSF
    Polyclonal Antibody for Human G-CSF
    Polyclonal Antibody for Human G-CSF
    Cat.:
    P0042Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human G-CSF
    Monoclonal Antibody for Human G-CSF
    Monoclonal Antibody for Human G-CSF
    Monoclonal Antibody for Human G-CSF
    Monoclonal Antibody for Human G-CSF
    Monoclonal Antibody for Human G-CSF
    Protein for Human G-CSF
    Protein for Human G-CSF
    Protein for Human G-CSF
    Protein for Human G-CSF
    Protein for Human G-CSF

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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor."
      Nagata S. , Tsuchiya M. , Asano S. , Kaziro Y. , Yamazaki T. , Yamamoto O. , Hirata Y. , Kubota N. , Oheda M. , Nomura H. , Ono M.
      Nature319:415-418(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
    2. 2.
      "The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor."
      Nagata S. , Tsuchiya M. , Asano S. , Yamamoto O. , Hirata Y. , Kubota N. , Oheda M. , Nomura H. , Yamazaki T.
      EMBO J.5:575-581(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM SHORT);ALTERNATIVE SPLICING
    3. 3.
      "Expression of granulocyte colony-stimulating factor by human cell lines."
      Devlin J.J. , Devlin P.E. , Myambo K. , Lilly M.B. , Rado T.A. , Warren M.K.
      J. Leukoc. Biol.41:302-306(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
    4. 4.
      SeattleSNPs variation discovery resource
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS MET-157 AND THR-174
    5. 5.
      "PCR isolation and cloning of novel splice variant mRNAs from known drug target genes."
      Jin P. , Fu G.K. , Wilson A.D. , Yang J. , Chien D. , Hawkins P.R. , Au-Young J. , Stuve L.L.
      Genomics83:566-571(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    6. 7.
      "Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells."
      Souza L.M. , Boone T.C. , Gabrilove J. , Lai P.H. , Zsebo K.M. , Murdock D.C. , Chazin V.R. , Bruszewski J. , Lu H. , Chen K.K. , Barendt J. , Platzer E. , Moore M.A.S. , Mertelsmann R. , Welte K.
      Science232:61-66(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 19-207 (ISOFORM SHORT)
    7. 8.
      "Extracellular domain of granulocyte-colony stimulating factor receptor. Interaction with its ligand and identification of a domain in close proximity of ligand-binding region."
      Haniu M. , Horan T. , Arakawa T. , Le J. , Katta V. , Rohde M.F.
      Arch. Biochem. Biophys.324:344-356(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-46
    8. 9.
      "Glycosidase digestion, electrophoresis and chromatographic analysis of recombinant human granulocyte colony-stimulating factor glycoforms produced in Chinese hamster ovary cells."
      Clogston C.L. , Hu S. , Boone T.C. , Lu H.S.
      J. Chromatogr. A637:55-62(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-166
    9. 10.
      "Secondary structure of human granulocyte colony-stimulating factor derived from NMR spectroscopy."
      Zink T. , Ross A. , Ambrosius D. , Rudolph R. , Holak T.A.
      FEBS Lett.314:435-439(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    10. 11.
      "Structure and dynamics of the human granulocyte colony-stimulating factor determined by NMR spectroscopy. Loop mobility in a four-helix-bundle protein."
      Zink T. , Ross A. , Luers K. , Cieslar C. , Rudolph R. , Holak T.A.
      Biochemistry33:8453-8463(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    11. 12.
      "The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors."
      Hill C.P. , Osslund T.D. , Eisenberg D.
      Proc. Natl. Acad. Sci. U.S.A.90:5167-5171(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
    12. 13.
      "Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme."
      Aritomi M. , Kunishima N. , Okamoto T. , Kuroki R. , Ota Y. , Morikawa K.
      Nature401:713-717(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 31-207 IN COMPLEX WITH CSF3R
    13. 14.
      "Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex."
      Tamada T. , Honjo E. , Maeda Y. , Okamoto T. , Ishibashi M. , Tokunaga M. , Kuroki R.
      Proc. Natl. Acad. Sci. U.S.A.103:3135-3140(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 31-207 IN COMPLEX WITH CSF3R
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