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Index > Protein center > CASKIN1(Gene name) > Human
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  • CASKIN1 (Gene name),
  • Caskin-1 (Protein name ),  CSKI1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CASKIN1(KIAA1306);
    Protein name:
    Caskin-1;
    Alternative:
    CASK-interacting protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds the CaM kinase domain of CASK. Forms a ternary complex with CASK and LIN7A, LIN7B or LIN7C. Competes with APBA1 that forms a similar complex with CASK and LIN7 proteins. The tripartite complex CASKIN1/CASK/LIN7(A/B/C) binds the cytoplasmic tail of NRXN1.
    Function:
    May link the scaffolding protein CASK to downstream intracellular effectors.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1431
    Sequence:
    50:
    MGKEQELVQA | VKAEDVGTAQ | RLLQRPRPGK | AKLLGSTKKI | NVNFQDPDGF | 
    100:
    SALHHAALNG | NTELISLLLE | AQAAVDIKDN | KGMRPLHYAA | WQGRKEPMKL | 
    150:
    VLKAGSAVNI | PSDEGHIPLH | LAAQHGHYDV | SEMLLQHQSN | PCMVDNSGKT | 
    200:
    PLDLACEFGR | VGVVQLLLSS | NMCAALLEPR | PGDATDPNGT | SPLHLAAKNG | 
    250:
    HIDIIRLLLQ | AGIDINRQTK | SGTALHEAAL | CGKTEVVRLL | LDSGINAHVR | 
    300:
    NTYSQTALDI | VHQFTTSQAS | REIKQLLREA | SAALQVRATK | DYCNNYDLTS | 
    350:
    LNVKAGDIIT | VLEQHPDGRW | KGCIHDNRTG | NDRVGYFPSS | LGEAIVKRAG | 
    400:
    SRAGTEPSLP | QGSSSSGPSA | PPEEIWVLRK | PFAGGDRSGS | ISGMAGGRGS | 
    450:
    GGHALHAGSE | GVKLLATVLS | QKSVSESGPG | DSPAKPPEGS | AGVARSQPPV | 
    500:
    AHAGQVYGEQ | PPKKLEPASE | GKSSEAVSQW | LTAFQLQLYA | PNFISAGYDL | 
    550:
    PTISRMTPED | LTAIGVTKPG | HRKKIAAEIS | GLSIPDWLPE | HKPANLAVWL | 
    600:
    SMIGLAQYYK | VLVDNGYENI | DFITDITWED | LQEIGITKLG | HQKKLMLAVR | 
    650:
    KLAELQKAEY | AKYEGGPLRR | KAPQSLEVMA | IESPPPPEPT | PADCQSPKMT | 
    700:
    TFQDSELSDE | LQAAMTGPAE | VGPTTEKPSS | HLPPTPRATT | RQDSSLGGRA | 
    750:
    RHMSSSQELL | GDGPPGPSSP | MSRSQEYLLD | EGPAPGTPPR | EARPGRHGHS | 
    800:
    IKRASVPPVP | GKPRQVLPPG | TSHFTPPQTP | TKTRPGSPQA | LGGPHGPAPA | 
    850:
    TAKVKPTPQL | LPPTERPMSP | RSLPQSPTHR | GFAYVLPQPV | EGEVGPAAPG | 
    900:
    PAPPPVPTAV | PTLCLPPEAD | AEPGRPKKRA | HSLNRYAASD | SEPERDELLV | 
    950:
    PAAAGPYATV | QRRVGRSHSV | RAPAGADKNV | NRSQSFAVRP | RKKGPPPPPP | 
    1000:
    KRSSSALASA | NLADEPVPDA | EPEDGLLGVR | AQCRRASDLA | GSVDTGSAGS | 
    1050:
    VKSIAAMLEL | SSIGGGGRAA | RRPPEGHPTP | RPASPEPGRV | ATVLASVKHK | 
    1100:
    EAIGPGGEVV | NRRRTLSGPV | TGLLATARRG | PGESADPGPF | VEDGTGRQRP | 
    1150:
    RGPSKGEAGV | EGPPLAKVEA | SATLKRRIRA | KQNQQENVKF | ILTESDTVKR | 
    1200:
    RPKAKEREAG | PEPPPPLSVY | HNGTGTVRRR | PASEQAGPPE | LPPPPPPAEP | 
    1250:
    PPTDLAHLPP | LPPPEGEARK | PAKPPVSPKP | VLTQPVPKLQ | GSPTPTSKKV | 
    1300:
    PLPGPGSPEV | KRAHGTPPPV | SPKPPPPPTA | PKPVKAVAGL | PSGSAGPSPA | 
    1350:
    PSPARQPPAA | LAKPPGTPPS | LGASPAKPPS | PGAPALHVPA | KPPRAAAAAA | 
    1400:
    AAAAAPPAPP | EGASPGDSAR | QKLEETSACL | AAALQAVEEK | IRQEDAQGPR | 
    1431:
    DSAAEKSTGS | ILDDIGSMFD | DLADQLDAML | E
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    Pfam:
    String:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Caskin-1
    ELISA Kit for Human Caskin-1
    ELISA Kit for Human Caskin-1
    CLIA Kit for Human Caskin-1
    CLIA Kit for Human Caskin-1
    CLIA Kit for Human Caskin-1
    Polyclonal Antibody for Human Caskin-1
    Polyclonal Antibody for Human Caskin-1
    Polyclonal Antibody for Human Caskin-1
    Monoclonal Antibody for Human Caskin-1
    Monoclonal Antibody for Human Caskin-1
    Monoclonal Antibody for Human Caskin-1
    Protein for Human Caskin-1
    Protein for Human Caskin-1
    Protein for Human Caskin-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with Caskin 1, a novel CASK-binding protein."
      Tabuchi K. , Biederer T. , Butz S. , Suedhof T.C.
      J. Neurosci.22:4264-4273(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Kikuno R. , Ishikawa K. , Hirosawa M. , Ohara O.
      DNA Res.7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 278-1431
      tissue: Brain.
    3. 3.
      "Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK."
      Stafford R.L. , Hinde E. , Knight M.J. , Pennella M.A. , Ear J. , Digman M.A. , Gratton E. , Bowie J.U.
      Structure19:1826-1836(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 470-605;SUBUNIT
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