Ctbp1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCtbp1 ELISA Kit for Rat(Rattus norvegicus)

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Ctbp1 (Gene name),

C-terminal-binding protein 1 (Protein name ), CTBP1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ctbp1(Bars;Ctbp3);

Protein name:

C-terminal-binding protein 1(CtBP1);

Alternative:

BARS-50;50 kDa BFA-dependent ADP-ribosylation substrate;C-terminal-binding protein 3(CtBP3);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer, or heterodimer of CTBP1 and CTBP2. Interacts with FOXP1, FOXP2, HIPK2, PNN and NRIP1. Interacts with ZFHX1B, HDAC4, HDAC5, HDAC9 and WIZ. Interacts with GLIS2 but not GLIS1 or GLIS3. Interacts with PRDM16; represses white adipose tissue (WAT)-specific genes expression. Interaction with non acetylated SATB1 stabalizes its attachment to DNA and promotes transcription repression (By similarity). Interacts with MECOM (By similarity). Interacts with ZNF217.

Function:

Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity. Functions in brown adipose tissue (BAT) differentiation.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

430

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

430:

LPPVAHPPHA | PSPGQTVKPE | ADRDHTTDQL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:29382

Pfam:

PF00389

String:

Q9Z2F5

UniGene:

Rn.3946

SMR:

Q9Z2F5

Uniprot:

Q9Z2F5

FOR

ELISA Kit for Rat CtBP1

CLIA Kit for Rat CtBP1

Polyclonal Antibody for Rat CtBP1

Monoclonal Antibody for Rat CtBP1

Protein for Rat CtBP1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure."
Spano S. , Silletta M.G. , Colanzi A. , Alberti S. , Fiucci G. , Valente C. , Fusella A. , Salmona M. , Mironov A. , Luini A. , Corda D.
J. Biol. Chem.274:17705-17710(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;SUBCELLULAR LOCATION
strain: Sprague-Dawley.
tissue: Brain.
2.

Spano S. , Silletta M.G. , Colanzi A. , Alberti S. , Fiucci G. , Valente C. , Fusella A. , Salmona M. , Mironov A. , Luini A. , Corda D.
J. Biol. Chem.274:25188-25188(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
3.

Spano S. , Silletta M.G. , Colanzi A. , Alberti S. , Fiucci G. , Valente C. , Fusella A. , Salmona M. , Mironov A. , Luini A. , Corda D.
Submitted (2001-05) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 259
4.

Lubec G. , Diao W.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 275-294;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Hippocampus.
5.

"Evidence that the 50-kDa substrate of brefeldin A-dependent ADP-ribosylation binds GTP and is modulated by the G-protein beta gamma subunit complex."
Di Girolamo M. , Silletta M.G. , De Matteis M.A. , Braca A. , Colanzi A. , Pawlak D. , Rasenick M.M. , Luini A. , Corda D.
Proc. Natl. Acad. Sci. U.S.A.92:7065-7069(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ADP-RIBOSYLATION;SUBCELLULAR LOCATION
6.

"CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission."
Nardini M. , Spano S. , Cericola C. , Pesce A. , Massaro A. , Millo E. , Luini A. , Corda D. , Bolognesi M.
EMBO J.22:3122-3130(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 1-349 IN COMPLEX WITH NADH;FUNCTION;MUTAGENESIS OF ALA-41 AND VAL-55
7.

"Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins."
Quinlan K.G.R. , Nardini M. , Verger A. , Francescato P. , Yaswen P. , Corda D. , Bolognesi M. , Crossley M.
Mol. Cell. Biol.26:8159-8172(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.85 ANGSTROMS) OF 1-350 IN COMPLEX WITH NAD AND ZNF217;INTERACTION WITH ZNF217
8.

"CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization."
Nardini M. , Valente C. , Ricagno S. , Luini A. , Corda D. , Bolognesi M.
Biochem. Biophys. Res. Commun.381:70-74(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF 1-350 OF MUTANT GLU-172;NAD BINDING;SUBUNIT;MUTAGENESIS OF GLY-172

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