Protein name:
C-terminal-binding protein 2 (CtBP2) ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with HIPK2, ZNF217 and PNN (By similarity). Interacts with the transcription factors BKLF, delta EF1/AREB6/ZEB, EVI-1 and Friend of GATA (FOG) via the consensus motif P-X-[DNS]-L-[STVA]. Can form a complex with BKLF on a CACCC-box oligonucleotide. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with NRIP1 and WIZ. Interacts with PRDM16; represses white adipose tissue (WAT)-specific genes expression.
Function:
Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation. Isoform 2 probably acts as a scaffold for specialized synapses.
Subcellular Location:
Nucleus
Cell junction
synapse
Protein Attributes:
50:
MALVDKHKVK | RQRLDRICEG | IRPQIMNGPL | HPRPLVALLD | GRDCTVEMPI |
100:
LKDLATVAFC | DAQSTQEIHE | KVLNEAVGAM | MYHTITLTRE | DLEKFKALRV |
150:
IVRIGSGYDN | VDIKAAGELG | IAVCNIPSAA | VEETADSTVC | HILNLYRRNT |
200:
WLYQALREGT | RVQSVEQIRE | VASGAARIRG | ETLGLIGFGR | TGQAVAVRAK |
250:
AFGFSVIFYD | PYLQDGIERS | LGVQRVYTLQ | DLLYQSDCVS | LHCNLNEHNH |
300:
HLINDFTIKQ | MRQGAFLVNA | ARGGLVDEKA | LAQALKEGRI | RGAALDVHES |
350:
EPFSFAQGPL | KDAPNLICTP | HTAWYSEQAS | LEMREAAATE | IRRAITGRIP |
400:
ESLRNCVNKE | FFVTSTPWSV | IDQQAIHPEL | NGATYRYPPG | IVGVAPGGLP |
445:
PAMEGIIPGG | IPVTHNLPTV | AHPSQAPSPN | QPTKHGDNRE | HPNEQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
Polyclonal Antibody for Rat CtBP2
Polyclonal Antibody for Rat CtBP2
Polyclonal Antibody for Rat CtBP2
Polyclonal Antibody for Rat CtBP2
Monoclonal Antibody for Rat CtBP2
Monoclonal Antibody for Rat CtBP2
Monoclonal Antibody for Rat CtBP2
Monoclonal Antibody for Rat CtBP2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
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Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .