Gene name:
CTC1 (C17orf68) ;
Protein name:
CST complex subunit CTC1 ;
Alternative:
HBV DNAPTP1-transactivated protein B ;Conserved telomere maintenance component 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of the CST complex, composed of TEN1/C17orf106, CTC1/C17orf68 and STN1/OBFC1. Interacts with STN1/OBFC1; the interaction is direct.
Function:
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Subcellular Location:
Nucleus
Chromosome
telomere
A transmembrane region is predicted by sequence analysis tools (ESKW, MEMSAT and Phobius); however, given the telomeric localization of the protein, the relevance of the transmembrane region is unsure in vivo.
Protein Attributes:
50:
MAAGRAQVPS | SEQAWLEDAQ | VFIQKTLCPA | VKEPNVQLTP | LVIDCVKTVW |
100:
LSQGRNQGST | LPLSYSFVSV | QDLKTHQRLP | CCSHLSWSSS | AYQAWAQEAG |
150:
PNGNPLPREQ | LLLLGTLTDL | SADLEQECRN | GSLYVRDNTG | VLSCELIDLD |
200:
LSWLGHLFLF | PRWSYLPPAR | WNSSGEGHLE | LWDAPVPVFP | LTISPGPVTP |
250:
IPVLYPESAS | CLLRLRNKLR | GVQRNLAGSL | VRLSALVKSK | QKAYFILSLG |
300:
RSHPAVTHVS | IIVQVPAQLV | WHRALRPGTA | YVLTELRVSK | IRGQRQHVWM |
350:
TSQSSRLLLL | KPECVQELEL | ELEGPLLEAD | PKPLPMPSNS | EDKKDPESLV |
400:
RYSRLLSYSG | AVTGVLNEPA | GLYELDGQLG | LCLAYQQFRG | LRRVMRPGVC |
450:
LQLQDVHLLQ | SVGGGTRRPV | LAPCLRGAVL | LQSFSRQKPG | AHSSRQAYGA |
500:
SLYEQLVWER | QLGLPLYLWA | TKALEELACK | LCPHVLRHHQ | FLQHSSPGSP |
550:
SLGLQLLAPT | LDLLAPPGSP | VRNAHNEILE | EPHHCPLQKY | TRLQTPSSFP |
600:
TLATLKEEGQ | RKAWASFDPK | ALLPLPEASY | LPSCQLNRRL | AWSWLCLLPS |
650:
AFCPAQVLLG | VLVASSHKGC | LQLRDQSGSL | PCLLLAKHSQ | PLSDPRLIGC |
700:
LVRAERFQLI | VERDVRSSFP | SWKELSMPGF | IQKQQARVYV | QFFLADALIL |
750:
PVPRPCLHSA | TPSTPQTDPT | GPEGPHLGQS | RLFLLCHKEA | LMKRNFCVPP |
800:
GASPEVPKPA | LSFYVLGSWL | GGTQRKEGTG | WGLPEPQGND | DNDQKVHLIF |
850:
FGSSVRWFEF | LHPGQVYRLI | APGPATPMLF | EKDGSSCISR | RPLELAGCAS |
900:
CLTVQDNWTL | ELESSQDIQD | VLDANKSLPE | SSLTDLLSDN | FTDSLVSFSA |
950:
EILSRTLCEP | LVASLWMKLG | NTGAMRRCVK | LTVALETAEC | EFPPHLDVYI |
1000:
EDPHLPPSLG | LLPGARVHFS | QLEKRVSRSH | NVYCCFRSST | YVQVLSFPPE |
1050:
TTISIPLPHI | YLAELLQGGQ | SPFQATASCH | IVSVFSLQLF | WVCAYCTSIC |
1100:
RQGKCTRLGS | TCPTQTAISQ | AIIRLLVEDG | TAEAVVTCRN | HHVAAALGLC |
1150:
PREWASLLDF | VQVPGRVVLQ | FAGPGAQLES | SARVDEPMTM | FLWTLCTSPS |
1200:
VLRPIVLSFE | LERKPSKIVP | LEPPRLQRFQ | CGELPFLTHV | NPRLRLSCLS |
1217:
IRESEYSSSL | GILASSC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human CST complex subunit CTC1
ELISA Kit for Human CST complex subunit CTC1
CLIA Kit for Human CST complex subunit CTC1
CLIA Kit for Human CST complex subunit CTC1
Polyclonal Antibody for Human CST complex subunit CTC1
Polyclonal Antibody for Human CST complex subunit CTC1
Monoclonal Antibody for Human CST complex subunit CTC1
Monoclonal Antibody for Human CST complex subunit CTC1
Protein for Human CST complex subunit CTC1
Protein for Human CST complex subunit CTC1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT VAL-1005
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-1005
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-1005
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Uterine adenocarcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE CST COMPLEX;SUBCELLULAR LOCATION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS CRMCC VAL-227; GLY-665; GLY-975; CYS-985 DEL; HIS-1142 AND 1196-LEU--ARG-1202 DEL
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS CRMCC MET-259; ARG-503; TRP-840; MET-871; GLY-975; CYS-985 DEL; TRP-987 AND 1196-LEU--ARG-1202 DEL