Ctif ELISA Kit for Mouse(Mus musculus) | EIAab.comCtif ELISA Kit for Mouse(Mus musculus)

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Ctif (Gene name),

CBP80/20-dependent translation initiation factor (Protein name ), CTIF_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ctif(Gm672;Kiaa0427);

Protein name:

CBP80/20-dependent translation initiation factor;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with NCBP1/CBP80; the interaction is direct. Associates with the eukaryotic translation initiation factor 3 (eIF-3) complex.

Function:

Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD).

Subcellular Location:

Cytoplasm perinuclear region

Protein Attributes:

Sequence length:

600

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:269037

SMR:

Q6PEE2

Pfam:

PF02854

UniGene:

Mm.36745

Uniprot:

Q6PEE2

FOR

ELISA Kit for Mouse CBP80/20-dependent translation initiation factor

CLIA Kit for Mouse CBP80/20-dependent translation initiation factor

Polyclonal Antibody for Mouse CBP80/20-dependent translation initiation factor

Monoclonal Antibody for Mouse CBP80/20-dependent translation initiation factor

Protein for Mouse CBP80/20-dependent translation initiation factor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: C57BL/6.
tissue: Brain.
2.

"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 334-600 (ISOFORM 1)
tissue: Pancreatic islet.
3.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
4.

"A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation."
Kim K.M. , Cho H. , Choi K. , Kim J. , Kim B.-W. , Ko Y.-G. , Jang S.K. , Kim Y.K.
Genes Dev.23:2033-2045(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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