CXCR3 ELISA Kit for Human(Homo sapiens) | EIAab.comCXCR3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CXCR3(Gene name) > Human

CXCR3 (Gene name),

C-X-C chemokine receptor type 3 (Protein name ), CXCR3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CXCR3(GPR9);

Protein name:

C-X-C chemokine receptor type 3(CXC-R3;CXCR-3);

Alternative:

G protein-coupled receptor 9;CKR-L2;Interferon-inducible protein 10 receptor(IP-10 receptor);

CD:

CD183;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Isoform 3 mediates the activity of CXCL11.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

368

Sequence:

50:

100:

150:

200:

250:

300:

350:

368:

SRRDSSWSET | SEASYSGL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P49682

KEGG:

hsa:2833

UniGene:

Hs.198252

MIM:

300574

Pfam:

PF00001

SMR:

P49682

STRING:

9606.ENSP00000362795

Uniprot:

P49682

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ELISA Kit for Human CXC-R3

Cat.:

E0625h

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Manual:

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Packing:

96T

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ELISA Kit for Human CXC-R3

Cat.:

E0625r

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MSDS:

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Packing:

96T

ELISA Kit for Human CXC-R3

Cat.:

E0625m

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MSDS:

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Packing:

96T

ELISA Kit for Human CXC-R3

Cat.:

E0625d

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MSDS:

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Packing:

96T

ELISA Kit for Human CXC-R3

Cat.:

E0625b

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MSDS:

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Packing:

96T

CLIA Kit for Human CXC-R3

Cat.:

U0625m

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MSDS:

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Packing:

96T

CLIA Kit for Human CXC-R3

Cat.:

U0625r

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human CXC-R3

Cat.:

U0625h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human CXC-R3

Cat.:

U0625d

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CXC-R3

Cat.:

U0625b

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human CXC-R3

Cat.:

P0625Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CXC-R3

Cat.:

P0625Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CXC-R3

Cat.:

P0625Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human CXC-R3

Protein for Human CXC-R3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes."
Loetscher M. , Gerber B. , Loetscher P. , Jones S.A. , Piali L. , Clark-Lewis I. , Baggiolini M. , Moser B.
J. Exp. Med.184:963-969(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Blood.
2.

"An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4."
Lasagni L. , Francalanci M. , Annunziato F. , Lazzeri E. , Giannini S. , Cosmi L. , Sagrinati C. , Mazzinghi B. , Orlando C. , Maggi E. , Marra F. , Romagnani S. , Serio M. , Romagnani P.
J. Exp. Med.197:1537-1549(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
3.

"Activation of p38(MAPK) mediates the angiostatic effect of the chemokine receptor CXCR3-B."
Petrai I. , Rombouts K. , Lasagni L. , Annunziato F. , Cosmi L. , Romanelli R.G. , Sagrinati C. , Mazzinghi B. , Pinzani M. , Romagnani S. , Romagnani P. , Marra F.
Int. J. Biochem. Cell Biol.40:1764-1774(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION
tissue: Endothelial cell.
tissue: Thymus.
4.

Gutierrez J. , Varona R. , Zaballos A. , Lind P. , Marquez G.
Submitted (1996-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2)
5.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Warren C.N. , Aronstam R.S. , Sharma S.V.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Leukocyte.
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Colon.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
tissue: Lung.
tissue: Testis.
8.

"Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors."
Marchese A. , Heiber M. , Nguyen T. , Heng H.H.Q. , Saldivia V.R. , Cheng R. , Murphy P.M. , Tsui L.-C. , Shi X. , Gregor P. , George S.R. , O'Dowd B.F. , Docherty J.M.
Genomics29:335-344(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 5-368
9.

"Single nucleotide polymorphisms in the coding regions of human CXC-chemokine receptors CXCR1, CXCR2 and CXCR3."
Kato H. , Tsuchiya N. , Tokunaga K.
Genes Immun.1:330-337(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 278-368;VARIANTS GLN-292 AND THR-363
10.

"Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping."
Ehlert J.E. , Addison C.A. , Burdick M.D. , Kunkel S.L. , Strieter R.M.
J. Immunol.173:6234-6240(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 3);FUNCTION
11.

"Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3."
Cole K.E. , Strick C.A. , Paradis T.J. , Ogborne K.T. , Loetscher M. , Gladue R.P. , Lin W. , Boyd J.G. , Moser B. , Wood D.E. , Sahagan B.G. , Neote K.
J. Exp. Med.187:2009-2021(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING
tissue: Fetal astrocyte.
12.

"CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis."
Colvin R.A. , Campanella G.S. , Manice L.A. , Luster A.D.
Mol. Cell. Biol.26:5838-5849(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SULFATION AT TYR-27;MUTAGENESIS OF 1-MET--VAL-16; GLU-4; GLU-21; TYR-27; 27-TYR--TYR-29; TYR-29; ASP-112; ARG-197; ARG-212; ARG-216; ASP-278; ASP-282 AND GLU-293
13.

"Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10."
Gao J.M. , Xiang R.L. , Jiang L. , Li W.H. , Feng Q.P. , Guo Z.J. , Sun Q. , Zeng Z.P. , Fang F.D.
Acta Pharmacol. Sin.30:193-201(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SULFATION AT TYR-27 AND TYR-29;MUTAGENESIS OF TYR-27 AND TYR-29
14.

"CXCR3-B can mediate growth-inhibitory signals in human renal cancer cells by down-regulating the expression of heme oxygenase-1."
Datta D. , Banerjee P. , Gasser M. , Waaga-Gasser A.M. , Pal S.
J. Biol. Chem.285:36842-36848(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR."
Vinet J. , van Zwam M. , Dijkstra I.M. , Brouwer N. , van Weering H.R. , Watts A. , Meijer M. , Fokkens M.R. , Kannan V. , Verzijl D. , Vischer H.F. , Smit M.J. , Leurs R. , Biber K. , Boddeke H.W.
Br. J. Pharmacol.168:1375-1387(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;TISSUE SPECIFICITY

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