CYFIP2 ELISA Kit for Human(Homo sapiens) | EIAab.comCYFIP2 ELISA Kit for Human(Homo sapiens)

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CYFIP2 (Gene name),

Cytoplasmic FMR1-interacting protein 2 (Protein name ), CYFP2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CYFIP2(KIAA1168;PIR121);

Protein name:

Cytoplasmic FMR1-interacting protein 2;

Alternative:

p53-inducible protein 121;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with FMR1, FXR1 AND FXR2. Component of the WAVE1 complex composed of ABI2, CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1.

Function:

Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA.

Subcellular Location:

Cytoplasm Cytoplasm perinuclear region Cell junction synapse synaptosome Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus.

Protein Attributes:

Sequence length:

1278

Sequence:

50:

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1150:

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1250:

1278:

KSVETDSSTV | EHVRCFQPPI | HQSLATTC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

606323

UniGene:

Hs.519702

Pfam:

PF05994

KEGG:

hsa:26999

STRING:

9606.ENSP00000390948

String:

Q96F07

Uniprot:

Q96F07

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ELISA Kit for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

E15258m

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Packing:

96T

ELISA Kit for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

E15258h

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Packing:

96T

CLIA Kit for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

U15258m

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MSDS:

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Packing:

96T

CLIA Kit for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

U15258h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

P15258Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Cytoplasmic FMR1-interacting protein 2

Cat.:

P15258Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Cytoplasmic FMR1-interacting protein 2

Protein for Human Cytoplasmic FMR1-interacting protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Increased apoptosis induction by 121F mutant p53."
Saller E. , Tom E. , Brunori M. , Otter M. , Estreicher A. , Mack D.H. , Iggo R.
EMBO J.18:4424-4437(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION
2.

"Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."
Hirosawa M. , Nagase T. , Ishikawa K. , Kikuno R. , Nomura N. , Ohara O.
DNA Res.6:329-336(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);RNA EDITING OF POSITION 320
tissue: Brain.
3.

Ohara O. , Nagase T. , Kikuno R.
Submitted (2007-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
4.

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S. , Weil B. , Wellenreuther R. , Gassenhuber J. , Glassl S. , Ansorge W. , Boecher M. , Bloecker H. , Bauersachs S. , Blum H. , Lauber J. , Duesterhoeft A. , Beyer A. , Koehrer K. , Strack N. , Mewes H.-W. , Ottenwaelder B. , Obermaier B. , more...
Genome Res.11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);RNA EDITING OF POSITION 320
tissue: Amygdala.
5.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Lymph.
9.

"CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion."
Mayne M. , Moffatt T. , Kong H. , McLaren P.J. , Fowke K.R. , Becker K.G. , Namaka M. , Schenck A. , Bardoni B. , Bernstein C.N. , Melanson M.
Eur. J. Immunol.34:1217-1227(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAC1;TISSUE SPECIFICITY
10.

"Evolutionarily conserved human targets of adenosine to inosine RNA editing."
Levanon E.Y. , Hallegger M. , Kinar Y. , Shemesh R. , Djinovic-Carugo K. , Rechavi G. , Jantsch M.F. , Eisenberg E.
Nucleic Acids Res.33:1162-1168(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RNA EDITING OF POSITION 320
11.

"CYFIP2, a direct p53 target, is leptomycin-B sensitive."
Jackson R.S. II , Cho Y.-J. , Stein S. , Liang P.
Cell Cycle6:95-103(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION
12.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1062;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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