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Index > Protein center > CST1(Gene name) > Human
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  • CST1 (Gene name),
  • Cystatin-SN (Protein name ),  CYTN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CST1;
    Protein name:
    Cystatin-SN;
    Alternative:
    Cystatin-1;Cystain-SA-I;Salivary cystatin-SA-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    141
    Sequence:
    50:
    MAQYLSTLLL | LLATLAVALA | WSPKEEDRII | PGGIYNADLN | DEWVQRALHF | 
    100:
    AISEYNKATK | DDYYRRPLRV | LRARQQTVGG | VNYFFDVEVG | RTICTKSQPN | 
    141:
    LDTCAFHEQP | ELQKKQLCSF | EIYEVPWENR | RSLVKSRCQE | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cystatin-SN
    Cat.:
    E13950h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cystatin-SN
    Cat.:
    U13950h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cystatin-SN
    Cat.:
    P13950Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cystatin-SN
    Protein for Human Cystatin-SN

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family."
      Saitoh E. , Kim H.-S. , Smithies O. , Maeda N.
      Gene61:329-338(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT HIS-4
    2. 2.
      "Purification, molecular cloning, and sequencing of salivary cystatin SA-1."
      Al-Hashimi I. , Dickinson D.P. , Levine M.J.
      J. Biol. Chem.263:9381-9387(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT HIS-4
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    5. 5.
      "Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes."
      Saitoh E. , Isemura S. , Sanada K. , Kim H.-S. , Smithies O. , Maeda N.
      Biol. Chem. Hoppe-Seyler369:191-197(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-141
    6. 6.
      "Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S."
      Isemura S. , Saitoh E. , Sanada K. , Minakata K.
      J. Biochem.110:648-654(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-40
      tissue: Saliva.
    7. 7.
      "Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting."
      Ghafouri B. , Stahlbom B. , Tagesson C. , Lindahl M.
      Proteomics2:112-120(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-32
    8. 8.
      "Characterization of a new cysteine proteinase inhibitor of human saliva, cystatin SN, which is immunologically related to cystatin S."
      Isemura S. , Saitoh E. , Sanada K.
      FEBS Lett.198:145-149(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-141
    9. 9.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-35
    10. 10.
      "Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry."
      Ryan C.M. , Souda P. , Halgand F. , Wong D.T. , Loo J.A. , Faull K.F. , Whitelegge J.P.
      J. Am. Soc. Mass Spectrom.21:908-917(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MASS SPECTROMETRY
      tissue: Saliva.
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