Protein name:
Cytoplasmic dynein 1 intermediate chain 1 ;
Alternative:
Dynein intermediate chain 1, cytosolic (DH IC-1) ;Cytoplasmic dynein intermediate chain 1 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1H1. Interacts with DYNLT1 and DYNLT3. Interacts with DCTN1.
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Subcellular Location:
Cytoplasm
Chromosome
centromere
kinetochore
Cytoplasm
cytoskeleton
spindle pole
Protein Attributes:
50:
MSDKSDLKAE | LERKKQRLAQ | IREEKKRKEE | ERKKKEADMQ | QKKEPVPDDS |
100:
DLDRKRRETE | ALLQSIGISP | EPPLVPTPMS | PSSKSVSTPS | EAGSQDSGDL |
150:
GPLTRRRLHK | LGVSKITQVD | FLPREVVSYS | KETQTPLATH | QSEEDEDDEE |
200:
MVEPKGDQDS | EQENEDKKQE | VKEAPPRELT | EEEKQQILHS | EEFLIFFDRT |
250:
IRVIERALAE | DSDIFFDYSG | RELEEKDGDV | QAGANLSFNR | QFYDEHWSKH |
300:
RVVTCMDWSL | QYPELMVASY | NNNEDAPHEP | DGVALVWNMK | FKKTTPEYVF |
350:
HCQSSVMSVC | FARFHPNLVV | GGTYSGQIVL | WDNRSHRRTP | VQRTPLSAAA |
400:
HTHPVYCVNV | VGTQNAHNLI | TVSTDGKMCS | WSLDMLSTPQ | ESMELVYNKS |
450:
KPVAVTGMAF | PTGDVNNFVV | GSEEGTVYTA | CRHGSKAGIG | EVFEGHQGPV |
500:
TGINCHMAVG | PIDFSHLFVT | SSFDWTVKLW | TTKHNKPLYS | FEDNADYVYD |
550:
VMWSPVHPAL | FACVDGMGRL | DLWNLNNDTE | VPTASVAIEG | ASALNRVRWA |
600:
QGGKEVAVGD | SEGRIWIYDV | GELAVPHNDE | WTRFARTLVE | IRANRADSEE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Bovine
Mouse
Human
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 1
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 1
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 1
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 1
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 1
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE CYTOPLASMIC DYNEIN 1 COMPLEX