Dync1i1 ELISA Kit for Mouse(Mus musculus) | EIAab.comDync1i1 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Dync1i1(Gene name) > Mouse

Dync1i1 (Gene name),

Cytoplasmic dynein 1 intermediate chain 1 (Protein name ), DC1I1_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Dync1i1(Dnci1;Dncic1);

Protein name:

Cytoplasmic dynein 1 intermediate chain 1;

Alternative:

Dynein intermediate chain 1, cytosolic(DH IC-1);Cytoplasmic dynein intermediate chain 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1H1. Interacts with DYNLT1 and DYNLT3. Interacts with DCNT1 (By similarity). Interacts with DYNLL2.

Function:

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

Subcellular Location:

Cytoplasm Chromosome centromere kinetochore Cytoplasm cytoskeleton spindle pole

Protein Attributes:

Sequence length:

628

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

628:

WTRFARTLVE | IRANRADSEE | EGAVELAA

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:13426

Pfam:

PF00400

SMR:

O88485

Pfam:

PF11540

UniGene:

Mm.20893

String:

O88485

Uniprot:

O88485

FOR

ELISA Kit for Mouse Cytoplasmic dynein 1 intermediate chain 1

CLIA Kit for Mouse Cytoplasmic dynein 1 intermediate chain 1

Polyclonal Antibody for Mouse Cytoplasmic dynein 1 intermediate chain 1

Monoclonal Antibody for Mouse Cytoplasmic dynein 1 intermediate chain 1

Protein for Mouse Cytoplasmic dynein 1 intermediate chain 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human."
Crackower M.A. , Sinasac D.S. , Xia J. , Motoyama J. , Prochazka M. , Rommens J.M. , Scherer S.W. , Tsui L.-C.
Genomics55:257-267(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1A AND 1B)
2.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
4.

"The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif."
Lo K.W. , Naisbitt S. , Fan J.S. , Sheng M. , Zhang M.
J. Biol. Chem.276:14059-14066(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DYNLL2;MUTAGENESIS OF 151-LYS--THR-155
5.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.

Product Feedback Wall

* Email:
*Comments: