Protein name:
Cytoplasmic dynein 1 intermediate chain 2 ;
Alternative:
Dynein intermediate chain 2, cytosolic (DH IC-2) ;Cytoplasmic dynein intermediate chain 2 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNLT1 and DYNLT3. Interacts with DCNT1.
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Subcellular Location:
Cytoplasm
cytoskeleton
Protein Attributes:
50:
MSDKSELKAE | LERKKQRLAQ | IREGKKRKEE | ERKKKETDQK | KEAVAPVQEE |
100:
SDLEKKRREA | EALLQSMGLT | AESPIVPPPM | SPSSKSVSTP | SEAGSQDSGD |
150:
GAVGSRRGPI | KLGMAKITQV | DFPPREIVTY | TKETQTPVMA | QPKEDEEEED |
200:
DVVTPKPPIE | PEEEKTLKKD | EESDSKAPPH | ELTEEEKQQI | LHSEEFLSFF |
250:
DHSTRIVERA | LSEQINIFFD | YSGRDLEDKE | GEIQAGAKLS | LNRQFFDERW |
300:
SKHRVVSCLD | WSSQYPELLV | ASYNNNEDAP | HEPDGVALVW | NMKYKKTTPE |
350:
YVFHCQSAVM | SATFAKFHPN | LVVGGTYSGQ | IVLWDNRSNK | RTPVQRTPLS |
400:
AAAHTHPVYC | VNVVGTQNAH | NLISISTDGK | ICSWSLDMLS | HPQDSMELVH |
450:
KQSKAVAVTS | MSFPVGDVNN | FVVGSEEGSV | YTACRHGSKA | GISEMFEGHQ |
500:
GPITGIHCHS | AVGAVDFSHL | FVTSSFDWTV | KLWTTKNNKP | LYSFEDNSDY |
550:
VYDVMWSPTH | PALFACVDGM | GRLDLWNLNN | DTEVPTASIS | VEGNPALNRV |
600:
RWTHSGREIA | VGDSEGQIVI | YDVGEQIAVP | RNDEWARFGR | TLAEINANRA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
Rat
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
ELISA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
CLIA Kit for Bovine Cytoplasmic dynein 1 intermediate chain 2
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Polyclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Monoclonal Antibody for Bovine Cytoplasmic dynein 1 intermediate chain 2
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 2
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 2
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 2
Protein for Bovine Cytoplasmic dynein 1 intermediate chain 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal muscle .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE CYTOPLASMIC DYNEIN 1 COMPLEX