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Index > Protein center > DEFA5(Gene name) > Human
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  • DEFA5 (Gene name),
  • Defensin-5 (Protein name ),  DEF5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    DEFA5(DEF5);
    Protein name:
    Defensin-5;
    Alternative:
    HD5(20-94);Defensin, alpha 5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    94
    Sequence:
    50:
    MRTIAILAAI | LLVALQAQAE | SLQERADEAT | TQKQSGEDNQ | DLAISFAGNG | 
    94:
    LSALRTSGSQ | ARATCYCRTG | RCATRESLSG | VCEISGRLYR | LCCR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Defensin-5
    Cat.:
    E1718m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Defensin-5
    Cat.:
    E1718h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Defensin-5
    Cat.:
    U1718h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Defensin-5
    Cat.:
    U1718m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Defensin-5
    Cat.:
    P1718Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Defensin-5
    Cat.:
    P1718Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Defensin-5
    Monoclonal Antibody for Human Defensin-5
    Protein for Human Defensin-5
    Protein for Human Defensin-5
    Cat.:
    R1718h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data
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    12% SDS-PAGE analysis

           12% SDS-PAGE analysis

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Paneth cells of the human small intestine express an antimicrobial peptide gene."
      Jones D.E. , Bevins C.L.
      J. Biol. Chem.267:23216-23225(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Intestine.
    2. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 5.
      "Paneth cell trypsin is the processing enzyme for human defensin-5."
      Ghosh D. , Porter E. , Shen B. , Lee S.K. , Wilk D. , Drazba J. , Yadav S.P. , Crabb J.W. , Ganz T. , Bevins C.L.
      Nat. Immunol.3:583-590(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;FUNCTION;PEPTIDE CHARACTERIZATION;GLYCOSYLATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    5. 6.
      "Antibacterial activity and specificity of the six human alpha-defensins."
      Ericksen B. , Wu Z. , Lu W. , Lehrer R.I.
      Antimicrob. Agents Chemother.49:269-275(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 7.
      "Crystal structures of human alpha-defensins HNP4, HD5, and HD6."
      Szyk A. , Wu Z. , Tucker K. , Yang D. , Lu W. , Lubkowski J.
      Protein Sci.15:2749-2760(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 63-94;FUNCTION;SUBUNIT;DISULFIDE BONDS
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