Dhx9 ELISA Kit for Mouse(Mus musculus) | EIAab.comDhx9 ELISA Kit for Mouse(Mus musculus)

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Dhx9 (Gene name),

ATP-dependent RNA helicase A (Protein name ), DHX9_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Dhx9(Ddx9);

Protein name:

ATP-dependent RNA helicase A(RHA);

Alternative:

Nuclear DNA helicase II(NDH II);DEAH box protein 9(mHEL-5);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the coding region determinant (CRD)-mediated complex, composed of DHX9, HNRNPU, IGF2BP1, SYNCRIP and YBX1. Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1. Binds MBD2, HRMT1L2/PRMT1, and RELA. May act to directly link BRCA1, CREBBP or SMN1 and the RNA polymerase II complex. Can also interact with XRCC5 and with TOP2A in an RNA dependent manner; these interactions may be indirect. Interaction with TOP2A is promoted by UBC9. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on 'Ser-139' (By similarity). Interacts with ZIC2.

Function:

Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator.

Subcellular Location:

Nucleus nucleolus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Can shuttle between nucleus and cytoplasm.

Protein Attributes:

Sequence length:

1380

Sequence:

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1250:

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1350:

1380:

GYRGSGGFQR | RGYGGGYFGQ | GRGGGGGGGY |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O70133

UniGene:

Mm.20000

Pfam:

PF00270

String:

O70133

KEGG:

mmu:13211

Uniprot:

O70133

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ELISA Kit for Mouse RHA

Cat.:

E2655h

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MSDS:

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Packing:

96T

ELISA Kit for Mouse RHA

Cat.:

E2655b

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MSDS:

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Packing:

96T

ELISA Kit for Mouse RHA

Cat.:

E2655m

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Packing:

96T

CLIA Kit for Mouse RHA

Cat.:

U2655h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse RHA

Cat.:

U2655b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse RHA

Cat.:

U2655m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse RHA

Cat.:

P2655Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse RHA

Cat.:

P2655Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse RHA

Protein for Mouse RHA

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular analysis of the cDNA and genomic DNA encoding mouse RNA helicase A."
Lee C.-G. , Eki T. , Okumura K. , da Costa Soares V. , Hurwitz J.
Genomics47:365-371(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-161
strain: 129/Sv.
2.

"Transcriptome analysis of mouse stem cells and early embryos."
Sharov A.A. , Piao Y. , Matoba R. , Dudekula D.B. , Qian Y. , VanBuren V. , Falco G. , Martin P.R. , Stagg C.A. , Bassey U.C. , Wang Y. , Carter M.G. , Hamatani T. , Aiba K. , Akutsu H. , Sharova L. , Tanaka T.S. , Kimber W.L. , more...
PLoS Biol.1:410-419(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-756 (ISOFORM 3)
strain: C57BL/6NCr.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-756 (ISOFORM 1)
strain: C57BL/6J.
tissue: Embryonic germ cell.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-264 (ISOFORM 2)
strain: C57BL/6J.
tissue: Embryo.
5.

"mHEL-5."
Kisielow P. , Miazek A.
Submitted (1997-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 386-919 (ISOFORMS 1/2/3)
strain: C57BL/6.
6.

"Nucleolar localization of murine nuclear DNA helicase II (RNA helicase A)."
Zhang S. , Herrmann C. , Grosse F.
J. Cell Sci.112:2693-2703(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
7.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-137 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
8.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-137 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
9.

"An antiviral response directed by PKR phosphorylation of the RNA helicase A."
Sadler A.J. , Latchoumanin O. , Hawkes D. , Mak J. , Williams B.R.
PLoS Pathog.5:E1000311-E1000311(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH EIF2AK2;PHOSPHORYLATION
10.

"Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex."
Padmanabhan K. , Robles M.S. , Westerling T. , Weitz C.J.
Science337:599-602(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CIRCADIAN RHYTHMS;IDENTIFICATION IN A LARGE PER COMPLEX
11.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-148;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
12.

"Solution structure of double-stranded RNA-binding motifs from hypothetical protein BAB28848."
RIKEN structural genomics initiative (RSGI)
Submitted (2004-11) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 4-262
13.

"Functional role of Zic2 phosphorylation in transcriptional regulation."
Ishiguro A. , Aruga J.
FEBS Lett.582:154-158(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZIC2

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