H2-DMb1 ELISA Kit for Mouse(Mus musculus) | EIAab.comH2-DMb1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > H2-DMb1(Gene name) > Mouse

H2-DMb1 (Gene name),

Class II histocompatibility antigen, M beta 1 chain (Protein name ), DMB_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

H2-DMb1(H-2Mb1;Mb);

Protein name:

Class II histocompatibility antigen, M beta 1 chain;

Alternative:

H2-M beta 1 chain;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer of an alpha chain (DMA) and a beta chain (DMB).

Function:

Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.

Subcellular Location:

Late endosome membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Localizes to late endocytic compartment. Associates with lysosome membranes.

Protein Attributes:

Sequence length:

261

Sequence:

50:

100:

150:

200:

250:

261:

LSGSTYPEGR | H

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.460938

String:

P35737

Pfam:

PF07654

SMR:

P35737

Uniprot:

P35737

FOR

ELISA Kit for Mouse Class II histocompatibility antigen, M beta 1 chain

CLIA Kit for Mouse Class II histocompatibility antigen, M beta 1 chain

Polyclonal Antibody for Mouse Class II histocompatibility antigen, M beta 1 chain

Monoclonal Antibody for Mouse Class II histocompatibility antigen, M beta 1 chain

Protein for Mouse Class II histocompatibility antigen, M beta 1 chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"New class II-like genes in the murine MHC."
Cho S. , Attaya M. , Monaco J.J.
Nature353:573-576(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
2.

"Genomic organization of a mouse MHC class II region including the H2-M and Lmp2 loci."
Peleraux A. , Karlsson L. , Chambers J. , Peterson P.A.
Immunogenetics43:204-214(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: BALB/c.
3.

"The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif."
Lindstedt R. , Liljedahl M. , Peleraux A. , Peterson P.A. , Karlsson L.
Immunity3:561-572(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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