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Index > Protein center > DRAM1(Gene name) > Human
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  • DRAM1 (Gene name),
  • DNA damage-regulated autophagy modulator protein 1 (Protein name ),  DRAM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    DRAM1(DRAM);
    Protein name:
    DNA damage-regulated autophagy modulator protein 1;
    Alternative:
    Damage-regulated autophagy modulator;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
    Subcellular Location:
    Lysosome membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    238
    Sequence:
    50:
    MLCFLRGMAF | VPFLLVTWSS | AAFIISYVVA | VLSGHVNPFL | PYISDTGTTP | 
    100:
    PESGIFGFMI | NFSAFLGAAT | MYTRYKIVQK | QNQTCYFSTP | VFNLVSLVLG | 
    150:
    LVGCFGMGIV | ANFQELAVPV | VHDGGALLAF | VCGVVYTLLQ | SIISYKSCPQ | 
    200:
    WNSLSTCHIR | MVISAVSCAA | VIPMIVCASL | ISITKLEWNP | REKDYVYHVV | 
    238:
    SAICEWTVAF | GFIFYFLTFI | QDFQSVTLRI | STEINGDI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    E3508h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    E3508m
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    U3508h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    U3508m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    P3508Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human DNA damage-regulated autophagy modulator protein 1
    Cat.:
    P3508Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human DNA damage-regulated autophagy modulator protein 1
    Monoclonal Antibody for Human DNA damage-regulated autophagy modulator protein 1
    Protein for Human DNA damage-regulated autophagy modulator protein 1
    Protein for Human DNA damage-regulated autophagy modulator protein 1

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 78-238 (ISOFORM 1)
      tissue: Placenta.
    2. 2.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Liver.
      tissue: Skin.
    4. 4.
      "DRAM, a p53-induced modulator of autophagy, is critical for apoptosis."
      Crighton D. , Wilkinson S. , O'Prey J. , Syed N. , Smith P. , Harrison P.R. , Gasco M. , Garrone O. , Crook T. , Ryan K.M.
      Cell126:121-134(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION
    5. 5.
      "p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death."
      Crighton D. , O'prey J. , Bell H.S. , Ryan K.M.
      Cell Death Differ.14:1071-1079(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
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