Ddx39b ELISA Kit for Mouse(Mus musculus) | EIAab.comDdx39b ELISA Kit for Mouse(Mus musculus)

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Ddx39b (Gene name),

Spliceosome RNA helicase Ddx39b (Protein name ), DX39B_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Ddx39b(Bat1;Bat1a;Uap56);

Protein name:

Spliceosome RNA helicase Ddx39b;

Alternative:

DEAD box protein UAP56;56 kDa U2AF65-associated protein;HLA-B-associated transcript 1 protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer, and heterodimer with DDX39A. Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Component of the spliceosome. Interacts directly with U2AF2. Interacts directly with THOC4 and is necessary for THOC4 recruitment to spliced mRNA. Interacts with RBM8A, RNPS1 and SRRM1. Interacts with FYTTD1/UIF and THOC1.

Function:

Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. The ATPase and helicase activities are not influenced by U2AF2 and THOC4.

Subcellular Location:

Nucleus Nucleus speckle

Protein Attributes:

Sequence length:

428

Sequence:

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