Gene name:
Ddx39b (Bat1;Bat1a;Uap56) ;
Protein name:
Spliceosome RNA helicase Ddx39b ;
Alternative:
ATP-dependent RNA helicase p47 ;56 kDa U2AF65-associated protein ;DEAD box protein Uap56 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer, and heterodimer with DDX39A. Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Component of the spliceosome. Interacts directly with U2AF2. Interacts directly with THOC4 and is necessary for THOC4 recruitment to spliced mRNA. Interacts with RBM8A, RNPS1 and SRRM1. Interacts with FYTTD1/UIF and THOC1.
Function:
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. The ATPase and helicase activities are not influenced by U2AF2 and THOC4.
Subcellular Location:
Nucleus
Nucleus speckle
Protein Attributes:
50:
MAENDVDNEL | LDYEDDEVET | AAGADGTEAP | AKKDVKGSYV | SIHSSGFRDF |
100:
LLKPELLRAI | VDCGFEHPSE | VQHECIPQAI | LGMDVLCQAK | SGMGKTAVFV |
150:
LATLQQLEPV | TGQVSVLVMC | HTRELAFQIS | KEYERFSKYM | PNVKVAVFFG |
200:
GLSIKKDEEV | LKKNCPHIVV | GTPGRILALA | RNKSLNLKHI | KHFILDECDK |
250:
MLEQLDMRRD | VQEIFRMTPH | EKQVMMFSAT | LSKEIRPVCR | KFMQDPMEIF |
300:
VDDETKLTLH | GLQQYYVKLK | DNEKNRKLFD | LLDVLEFNQV | VIFVKSVQRC |
350:
IALAQLLVEQ | NFPAIAIHRG | MPQEERLSRY | QQFKDFQRRI | LVATNLFGRG |
400:
MDIERVNIAF | NYDMPEDSDT | YLHRVARAGR | FGTKGLAITF | VSDENDAKIL |
428:
NDVQDRFEVN | ISELPDEIDI | SSYIEQTR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Rat
Chicken
Dog
Mouse
Human
Bovine
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
ELISA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
CLIA Kit for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Polyclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Monoclonal Antibody for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
Protein for Rat Spliceosome RNA helicase Ddx39b
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
Lewis .
3.
"Sequence analysis of the rat MHC class I region."
Walter L.
Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
Brown Norway .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .