Dync1h1 ELISA Kit for Mouse(Mus musculus) | EIAab.comDync1h1 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Dync1h1(Gene name) > Mouse

Dync1h1 (Gene name),

Cytoplasmic dynein 1 heavy chain 1 (Protein name ), DYHC1_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Dync1h1(Dhc1;Dnch1;Dnchc1;Dyhc);

Protein name:

Cytoplasmic dynein 1 heavy chain 1;

Alternative:

Dynein heavy chain, cytosolic;Cytoplasmic dynein heavy chain 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and dynein LCs assemble on the IC dimer. Interacts with DYNC1LI1; DYNC1LI1 and DYNC1LI2 bind mutually exclusive to DYNC1H1. Interacts with DYNC1LI2; DYNC1LI1 and DYNC1LI2 bind mutually exclusive to DYNC1H1. Interacts with DYNC1I2.

Function:

Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Subcellular Location:

Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

4644

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

2000:

2050:

2100:

2150:

2200:

2250:

2300:

2350:

2400:

2450:

2500:

2550:

2600:

2650:

2700:

2750:

2800:

2850:

2900:

2950:

3000:

3050:

3100:

3150:

3200:

3250:

3300:

3350:

3400:

3450:

3500:

3550:

3600:

3650:

3700:

3750:

3800:

3850:

3900:

3950:

4000:

4050:

4100:

4150:

4200:

4250:

4300:

4350:

4400:

4450:

4500:

4550:

4600:

4644:

SVVTLPVYLN | FTRADLIFTV | DFEIATKEDP | RSFYERGVAV | LCTE

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:13424

UniGene:

Mm.181430

String:

Q9JHU4

Pfam:

PF07728

SMR:

Q9JHU4

Uniprot:

Q9JHU4

FOR

ELISA Kit for Mouse Cytoplasmic dynein 1 heavy chain 1

CLIA Kit for Mouse Cytoplasmic dynein 1 heavy chain 1

Polyclonal Antibody for Mouse Cytoplasmic dynein 1 heavy chain 1

Monoclonal Antibody for Mouse Cytoplasmic dynein 1 heavy chain 1

Protein for Mouse Cytoplasmic dynein 1 heavy chain 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complete cDNA sequence of murine cytoplasmic dynein heavy chain."
Sasaki S. , Shionoya A. , Hirotsune S.
Submitted (2000-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: FVB.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
4.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-4281;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
5.

"Mutations in dynein link motor neuron degeneration to defects in retrograde transport."
Hafezparast M. , Klocke R. , Ruhrberg C. , Marquardt A. , Ahmad-Annuar A. , Bowen S. , Lalli G. , Witherden A.S. , Hummerich H. , Nicholson S. , Morgan P.J. , Oozageer R. , Priestley J.V. , Averill S. , King V.R. , Ball S. , Peters J. , Toda T. , more...
Science300:808-812(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LOA TYR-580;VARIANT CRA1 CYS-1055

Product Feedback Wall

* Email:
*Comments: