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Index > Protein center > MEAF6(Gene name) > Human
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  • MEAF6 (Gene name),
  • Chromatin modification-related protein MEAF6 (Protein name ),  EAF6_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    MEAF6(C1orf149;EAF6);
    Protein name:
    Chromatin modification-related protein MEAF6(MYST/Esa1-associated factor 6);
    Alternative:
    Sarcoma antigen NY-SAR-91;Esa1-associated factor 6 homolog(Protein EAF6 homolog;hEAF6);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5 and the subunits EP400, TRRAP, BRD8, EPC1, DMAP1, RUVBL1, RUVBL2, ING3, actin, ACTL6A, MORF4L1, MORF4L2, MRGBP, YEATS4, VPS72 and MEAF6. Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17. Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
    Function:
    Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
    Subcellular Location:
    Nucleus nucleolus
    Protein Attributes:
    Sequence length:
    191
    Sequence:
    50:
    MAMHNKAAPP | QIPDTRRELA | ELVKRKQELA | ETLANLERQI | YAFEGSYLED | 
    100:
    TQMYGNIIRG | WDRYLTNQKN | SNSKNDRRNR | KFKEAERLFS | KSSVTSAAAV | 
    150:
    SALAGVQDQL | IEKREPGSGT | ESDTSPDFHN | QENEPSQEDP | EDLDGSVQGV | 
    191:
    KPQKAASSTS | SGSHHSSHKK | RKNKNRHRID | LKLNKKPRAD | Y
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human MYST/Esa1-associated factor 6
    ELISA Kit for Human MYST/Esa1-associated factor 6
    ELISA Kit for Human MYST/Esa1-associated factor 6
    ELISA Kit for Human MYST/Esa1-associated factor 6
    CLIA Kit for Human MYST/Esa1-associated factor 6
    CLIA Kit for Human MYST/Esa1-associated factor 6
    CLIA Kit for Human MYST/Esa1-associated factor 6
    CLIA Kit for Human MYST/Esa1-associated factor 6
    Polyclonal Antibody for Human MYST/Esa1-associated factor 6
    Polyclonal Antibody for Human MYST/Esa1-associated factor 6
    Polyclonal Antibody for Human MYST/Esa1-associated factor 6
    Polyclonal Antibody for Human MYST/Esa1-associated factor 6
    Monoclonal Antibody for Human MYST/Esa1-associated factor 6
    Monoclonal Antibody for Human MYST/Esa1-associated factor 6
    Monoclonal Antibody for Human MYST/Esa1-associated factor 6
    Monoclonal Antibody for Human MYST/Esa1-associated factor 6
    Protein for Human MYST/Esa1-associated factor 6
    Protein for Human MYST/Esa1-associated factor 6
    Protein for Human MYST/Esa1-associated factor 6
    Protein for Human MYST/Esa1-associated factor 6

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    Precision
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    Linearity
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    References
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