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Index > Protein center > ECI2(Gene name) > Human
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  • ECI2 (Gene name),
  • Enoyl-CoA delta isomerase 2, mitochondrial (Protein name ),  ECI2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ECI2(DRS1;HCA88;PECI);
    Protein name:
    Enoyl-CoA delta isomerase 2, mitochondrial;
    Alternative:
    Delta(3),delta(2)-enoyl-CoA isomerase(D3,D2-enoyl-CoA isomerase);DRS-1;Dodecenoyl-CoA isomerase;Diazepam-binding inhibitor-related protein 1(DBI-related protein 1);Peroxisomal 3,2-trans-enoyl-CoA isomerase(pECI);Hepatocellular carcinoma-associated antigen 88;Renal carcinoma antigen NY-REN-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.
    Subcellular Location:
    Isoform 2 Peroxisome matrix
    Protein Attributes:
    Sequence length:
    394
    Sequence:
    50:
    MAMAYLAWRL | ARRSCPSSLQ | VTSFPVVQLH | MNRTAMRASQ | KDFENSMNQV | 
    100:
    KLLKKDPGNE | VKLKLYALYK | QATEGPCNMP | KPGVFDLINK | AKWDAWNALG | 
    150:
    SLPKEAARQN | YVDLVSSLSP | SLESSSQVEP | GTDRKSTGFE | TLVVTSEDGI | 
    200:
    TKIMFNRPKK | KNAINTEMYH | EIMRALKAAS | KDDSIITVLT | GNGDYYSSGN | 
    250:
    DLTNFTDIPP | GGVEEKAKNN | AVLLREFVGC | FIDFPKPLIA | VVNGPAVGIS | 
    300:
    VTLLGLFDAV | YASDRATFHT | PFSHLGQSPE | GCSSYTFPKI | MSPAKATEML | 
    350:
    IFGKKLTAGE | ACAQGLVTEV | FPDSTFQKEV | WTRLKAFAKL | PPNALRISKE | 
    394:
    VIRKREREKL | HAVNAEECNV | LQGRWLSDEC | TNAVVNFLSR | KSKL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    ELISA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    ELISA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    CLIA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    CLIA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    CLIA Kit for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Polyclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Polyclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Polyclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Monoclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Monoclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Monoclonal Antibody for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Protein for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Protein for Human Enoyl-CoA delta isomerase 2, mitochondrial
    Protein for Human Enoyl-CoA delta isomerase 2, mitochondrial

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression of a novel human cDNA related to the diazepam binding inhibitor."
      Suk K. , Kim Y.-H. , Hwang D.-Y. , Ihm S.-H. , Yoo H.J. , Lee M.-S.
      Biochim. Biophys. Acta1454:126-131(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT VAL-344
      tissue: Pancreatic islet.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Placenta.
    4. 4.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Bone marrow.
      tissue: Skin.
      tissue: Uterus.
    6. 6.
      "Characterization of PECI, a novel monofunctional D3,D2-enoyl-CoA isomerase of mammalian peroxisomes."
      Geisbrecht B.V. , Zhang D. , Schulz H. , Gould S.J.
      J. Biol. Chem.274:21797-21803(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-394 (ISOFORM 1);SUBCELLULAR LOCATION
    7. 7.
      "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies."
      Wang Y. , Han K.-J. , Pang X.-W. , Vaughan H.A. , Qu W. , Dong X.-Y. , Peng J.-R. , Zhao H.-T. , Rui J.-A. , Leng X.-S. , Cebon J. , Burgess A.W. , Chen W.-F.
      J. Immunol.169:1102-1109(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-394 (ISOFORM 1);VARIANT VAL-344
      tissue: Hepatoma.
    8. 8.
      "Antigens recognized by autologous antibody in patients with renal-cell carcinoma."
      Scanlan M.J. , Gordan J.D. , Williamson B. , Stockert E. , Bander N.H. , Jongeneel C.V. , Gure A.O. , Jaeger D. , Jaeger E. , Knuth A. , Chen Y.-T. , Old L.J.
      Int. J. Cancer83:456-464(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION AS A RENAL CANCER ANTIGEN
      tissue: Renal cell carcinoma.
    9. 9.
      "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing."
      Simpson J.C. , Wellenreuther R. , Poustka A. , Pepperkok R. , Wiemann S.
      EMBO Rep.1:287-292(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    10. 10.
      "Diazepam-binding inhibitor-related protein 1: a candidate autoantigen in acquired aplastic anemia patients harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells."
      Feng X. , Chuhjo T. , Sugimori C. , Kotani T. , Lu X. , Takami A. , Takamatsu H. , Yamazaki H. , Nakao S.
      Blood104:2425-2431(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    11. 11.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-51 AND LYS-92;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Solution structure of RSGI RUH-045, a human acyl-CoA binding protein."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2005-11) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 36-133
    14. 14.
      "The crystal structure of human peroxisomal delta3, delta2 enoyl-CoA isomerase (pECI)."
      Structural genomics consortium (SGC)
      Submitted (2009-02) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 138-394
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