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Index > Protein center > EDIL3(Gene name) > Human
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  • EDIL3 (Gene name),
  • EGF-like repeat and discoidin I-like domain-containing protein 3 (Protein name ),  EDIL3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    EDIL3(DEL1);
    Protein name:
    EGF-like repeat and discoidin I-like domain-containing protein 3;
    Alternative:
    Integrin-binding protein DEL1;Developmentally-regulated endothelial cell locus 1 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    480
    Sequence:
    50:
    MKRSVAVWLL | VGLSLGVPQF | GKGDICDPNP | CENGGICLPG | LADGSFSCEC | 
    100:
    PDGFTDPNCS | SVVEVASDEE | EPTSAGPCTP | NPCHNGGTCE | ISEAYRGDTF | 
    150:
    IGYVCKCPRG | FNGIHCQHNI | NECEVEPCKN | GGICTDLVAN | YSCECPGEFM | 
    200:
    GRNCQYKCSG | PLGIEGGIIS | NQQITASSTH | RALFGLQKWY | PYYARLNKKG | 
    250:
    LINAWTAAEN | DRWPWIQINL | QRKMRVTGVI | TQGAKRIGSP | EYIKSYKIAY | 
    300:
    SNDGKTWAMY | KVKGTNEDMV | FRGNIDNNTP | YANSFTPPIK | AQYVRLYPQV | 
    350:
    CRRHCTLRME | LLGCELSGCS | EPLGMKSGHI | QDYQITASSI | FRTLNMDMFT | 
    400:
    WEPRKARLDK | QGKVNAWTSG | HNDQSQWLQV | DLLVPTKVTG | IITQGAKDFG | 
    450:
    HVQFVGSYKL | AYSNDGEHWT | VYQDEKQRKD | KVFQGNFDND | THRKNVIDPP | 
    480:
    IYARHIRILP | WSWYGRITLR | SELLGCTEEE | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    KEGG:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    E6050h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    E6050m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    U6050h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    U6050m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    P6050Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Cat.:
    P6050Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Monoclonal Antibody for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Protein for Human EGF-like repeat and discoidin I-like domain-containing protein 3
    Protein for Human EGF-like repeat and discoidin I-like domain-containing protein 3

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor."
      Hidai C. , Zupancic T.J. , Penta K. , Mikhail A. , Kawana M. , Quertermous E.E. , Aoka Y. , Fukagawa M. , Matsui Y. , Platika D. , Auerbach R. , Hogan B.L.M. , Snodgrass R. , Quertermous T.
      Genes Dev.12:21-33(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);CHARACTERIZATION
      tissue: Embryonic lung.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Trachea.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
    5. 5.
      "The RGD finger of Del-1 is a unique structural feature critical for integrin binding."
      Schurpf T. , Chen Q. , Liu J.H. , Wang R. , Springer T.A. , Wang J.H.
      FASEB J.26:3412-3420(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 24-157;RGD MOTIF;DISULFIDE BONDS;CALCIUM-BINDING SITES;GLYCOSYLATION AT THR-73; THR-88 AND ASN-140
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