Protein name:
Eukaryotic translation initiation factor 2D (eIF2D) ;
Alternative:
Ligatin ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MFAKAFRVKS | NTAIKGSDRR | KLRADVTAAF | PALGTDQISE | LIPGKEELNV |
100:
VKLYVHKGDS | VTVYTSGGNP | ILFELEKNLY | PTVYTLWAYP | DILPTFITWP |
150:
LVLEKLVGGA | DLMLPGVVVP | PTGLPQVQQG | DLCAIALVGN | RAPVAIGVAA |
200:
MSTAQMLASG | LKGKGVSVLH | TYQDHLWRSG | DKSSPPAIAP | LDPTDSCEEK |
250:
VHLGLQGNLK | SLTLDGEEEN | GQVPLREASE | DTSSRAPSQD | SLDGKPLQEQ |
300:
MDDLLLRCFL | HALKSRVKKA | DLPLLTSTLL | GSHMFSCCPE | GQQLDIKKSS |
350:
YKKLSKFLQH | MQQEQIVQVK | ELSKGVESIV | AVDWRHPRIT | SFVIPEPSLT |
400:
SQTVQEVSRE | QPYLPPDIKS | LYCVPANMTQ | LFLESGHKKG | STLEGSEVRK |
450:
IITDYAKRNR | LVDADNRNLV | KLDPILCDCI | LEKNEQHLVT | KLPWDCLLTR |
500:
CLKNMQPAYQ | VTFPGQEPIL | KKGKLCPIDI | TLALKTYNKK | VTVVRNLETY |
550:
GLDPCSVAAI | LQQRCQASTI | VSPAPGAKDS | LQVQVQGNQI | HHLGQLLLEE |
570:
YRLPGKYIQG | LEKAPKPGKK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Mouse
Human
Rabbit
ELISA Kit for Mouse eIF2D
ELISA Kit for Mouse eIF2D
ELISA Kit for Mouse eIF2D
ELISA Kit for Mouse eIF2D
ELISA Kit for Mouse eIF2D
Polyclonal Antibody for Mouse eIF2D
Polyclonal Antibody for Mouse eIF2D
Polyclonal Antibody for Mouse eIF2D
Polyclonal Antibody for Mouse eIF2D
Polyclonal Antibody for Mouse eIF2D
Monoclonal Antibody for Mouse eIF2D
Monoclonal Antibody for Mouse eIF2D
Monoclonal Antibody for Mouse eIF2D
Monoclonal Antibody for Mouse eIF2D
Monoclonal Antibody for Mouse eIF2D
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
BALB/c .
strain :
C57BL/6J .
strain :
NOD .
tissue :
Adrenal gland .
tissue :
Cerebellum .
tissue :
Diencephalon .
tissue :
Embryo .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N .
tissue :
Colon .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-550