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Index > Protein center > Emb(Gene name) > Rat
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  • Emb (Gene name),
  • Embigin (Protein name ),  EMB_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Emb(Gp70);
    Protein name:
    Embigin;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May function as a regulator of cell/ECM interactions during development and in the homeostasis of normal adult tissues.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    328
    Sequence:
    50:
    MRSHTGLRAL | VAPGCSLLLL | YLLAATRPDR | AVGDPADSAF | TSLPVREEMM | 
    100:
    AKYANLSLET | YNISLTEQTR | VSEQNITLER | PSHLELECTF | TATEDVMSMN | 
    150:
    VTWKKDDALL | ETTDGFNTTK | MGDTLYSQYR | FTVFNSKQMG | KYSCFLGEEL | 
    200:
    RGTFNIRVPK | VHGKNKPLIT | YVGDSTVLKC | ECQNCLPLNW | TWYMSNGTAQ | 
    250:
    VPIDVHVNDK | FDINGSYANE | TKLKVKHLLE | EDGGSYWCRA | AFPLGESEEH | 
    300:
    IKLVVLSFMV | PLKPFLAIIA | EVILLVAIIL | LCEVYTQKKK | NDPDDGKEFE | 
    328:
    QIEQLKSDDS | NGIENNVPRY | RKTDSGDQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Embigin
    ELISA Kit for Rat Embigin
    ELISA Kit for Rat Embigin
    CLIA Kit for Rat Embigin
    CLIA Kit for Rat Embigin
    CLIA Kit for Rat Embigin
    Polyclonal Antibody for Rat Embigin
    Polyclonal Antibody for Rat Embigin
    Polyclonal Antibody for Rat Embigin
    Monoclonal Antibody for Rat Embigin
    Monoclonal Antibody for Rat Embigin
    Monoclonal Antibody for Rat Embigin
    Protein for Rat Embigin
    Protein for Rat Embigin
    Protein for Rat Embigin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Embigin, a developmentally expressed member of the immunoglobulin super family, is also expressed during regression of prostate and mammary gland."
      Guenette R. , Sridhar S. , Herley M. , Mooibroek M. , Wong P. , Tenniswood M.
      Dev. Genet.21:268-278(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Prostate.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    3. 3.
      "Interaction of the erythrocyte lactate transporter (monocarboxylate transporter 1) with an integral 70-kDa membrane glycoprotein of the immunoglobulin superfamily."
      Poole R.C. , Halestrap A.P.
      J. Biol. Chem.272:14624-14628(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 121-135;INTERACTION WITH SLC16A1;GLYCOSYLATION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    4. 4.
      Lubec G. , Kang S.U. , Lubec S.
      Submitted (2007-09) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 142-151; 165-179 AND 240-252;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
    5. 5.
      "Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)."
      Wilson M.C. , Meredith D. , Fox J.E. , Manoharan C. , Davies A.J. , Halestrap A.P.
      J. Biol. Chem.280:27213-27221(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC16A7
    6. 6.
      "A novel role for embigin to promote sprouting of motor nerve terminals at the neuromuscular junction."
      Lain E. , Carnejac S. , Escher P. , Wilson M.C. , Lomo T. , Gajendran N. , Brenner H.R.
      J. Biol. Chem.284:8930-8939(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    7. 7.
      "Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle."
      Wilson M.C. , Meredith D. , Bunnun C. , Sessions R.B. , Halestrap A.P.
      J. Biol. Chem.284:20011-20021(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SLC16A1;SUBCELLULAR LOCATION;TOPOLOGY
    8. 8.
      "The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein."
      Ovens M.J. , Manoharan C. , Wilson M.C. , Murray C.M. , Halestrap A.P.
      Biochem. J.431:217-225(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC16A7;FUNCTION
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