Protein name:
Alpha-enolase ;
Alternative:
Enolase 1 ;2-phospho-D-glycerate hydro-lyase ;Non-neural enolase (NNE) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding.
Function:
Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Subcellular Location:
Cytoplasm
Cell membrane
Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
Protein Attributes:
50:
MSILKIHARE | IFDSRGNPTV | EVDLYTAKGL | FRAAVPSGAS | TGIYEALELR |
100:
DNDKTRFMGK | GVSKAVEHIN | KTIAPALVSK | KLNVVEQEKI | DQLMIEMDGT |
150:
ENKSKFGANA | ILGVSLAVCK | AGAVEKGVPL | YRHIADLAGN | PEVILPVPAF |
200:
NVINGGSHAG | NKLAMQEFMI | LPVGASSFRE | AMRIGAEVYH | NLKNVIKEKY |
250:
GKDATNVGDE | GGFAPNILEN | KEALELLKSA | IAKAGYTDQV | VIGMDVAASE |
300:
FYRAGKYDLD | FKSPDDASRY | ITPDQLADLY | KSFIKDYPVV | SIEDPFDQDD |
350:
WDAWQKFTAT | AGIQVVGDDL | TVTNPKRIAK | AAGEKSCNCL | LLKVNQIGSV |
400:
TESLQACKLA | QSNGWGVMVS | HRSGETEDTF | IADLVVGLCT | GQIKTGAPCR |
434:
SERLAKYNQI | LRIEEELGSK | AKFAGRSFRN | PLAK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
Bovine
Rat
ELISA Kit for Rat Alpha-enolase
ELISA Kit for Rat Alpha-enolase
ELISA Kit for Rat Alpha-enolase
ELISA Kit for Rat Alpha-enolase
ELISA Kit for Rat Alpha-enolase
CLIA Kit for Rat Alpha-enolase
CLIA Kit for Rat Alpha-enolase
CLIA Kit for Rat Alpha-enolase
CLIA Kit for Rat Alpha-enolase
CLIA Kit for Rat Alpha-enolase
Polyclonal Antibody for Rat Alpha-enolase
Polyclonal Antibody for Rat Alpha-enolase
Polyclonal Antibody for Rat Alpha-enolase
Polyclonal Antibody for Rat Alpha-enolase
Polyclonal Antibody for Rat Alpha-enolase
Monoclonal Antibody for Rat Alpha-enolase
Monoclonal Antibody for Rat Alpha-enolase
Monoclonal Antibody for Rat Alpha-enolase
Monoclonal Antibody for Rat Alpha-enolase
Monoclonal Antibody for Rat Alpha-enolase
Protein for Rat Alpha-enolase
Protein for Rat Alpha-enolase
Protein for Rat Alpha-enolase
Protein for Rat Alpha-enolase
Protein for Rat Alpha-enolase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
tissue :
Brain .
tissue :
Liver .
2.
Takahashi Y.
Submitted (1986-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Heart .
tissue :
Pituitary .
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 10-28; 33-50; 72-103; 106-120; 163-179; 184-193; 203-228; 234-262; 270-281; 307-326; 336-394 AND 407-420;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Brain .
tissue :
Hippocampus .
tissue :
Spinal cord .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 46-57; 97-109; 245-262 AND 369-382;INTERACTION WITH PLG
tissue :
Embryonic brain .
6.
"Rat cDNA encoding alpha enolase (2-phospho-D-glycerate hydro-lyase) (non-neural enolase) (NNE)."
Bole-Feysot C.
,
Kelly P.A.
Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 93-153
tissue :
Lymphoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION OF ALPHA/GAMMA HETERODIMER
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;TISSUE SPECIFICITY