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Index > Protein center > Eno1(Gene name) > Rat
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  • Eno1 (Gene name),
  • Alpha-enolase (Protein name ),  ENOA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Eno1(Eno-1);
    Protein name:
    Alpha-enolase;
    Alternative:
    Enolase 1;2-phospho-D-glycerate hydro-lyase;Non-neural enolase(NNE);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding.
    Function:
    Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
    Subcellular Location:
    Cytoplasm Cell membrane Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
    Protein Attributes:
    Sequence length:
    434
    Sequence:
    50:
    MSILKIHARE | IFDSRGNPTV | EVDLYTAKGL | FRAAVPSGAS | TGIYEALELR | 
    100:
    DNDKTRFMGK | GVSKAVEHIN | KTIAPALVSK | KLNVVEQEKI | DQLMIEMDGT | 
    150:
    ENKSKFGANA | ILGVSLAVCK | AGAVEKGVPL | YRHIADLAGN | PEVILPVPAF | 
    200:
    NVINGGSHAG | NKLAMQEFMI | LPVGASSFRE | AMRIGAEVYH | NLKNVIKEKY | 
    250:
    GKDATNVGDE | GGFAPNILEN | KEALELLKSA | IAKAGYTDQV | VIGMDVAASE | 
    300:
    FYRAGKYDLD | FKSPDDASRY | ITPDQLADLY | KSFIKDYPVV | SIEDPFDQDD | 
    350:
    WDAWQKFTAT | AGIQVVGDDL | TVTNPKRIAK | AAGEKSCNCL | LLKVNQIGSV | 
    400:
    TESLQACKLA | QSNGWGVMVS | HRSGETEDTF | IADLVVGLCT | GQIKTGAPCR | 
    434:
    SERLAKYNQI | LRIEEELGSK | AKFAGRSFRN | PLAK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Alpha-enolase
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    E1449h
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    ELISA Kit for Rat Alpha-enolase
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    ELISA Kit for Rat Alpha-enolase
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    E1449m
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    ELISA Kit for Rat Alpha-enolase
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    E1449b
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    ELISA Kit for Rat Alpha-enolase
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    E1449r
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    CLIA Kit for Rat Alpha-enolase
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    U1449c
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    CLIA Kit for Rat Alpha-enolase
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    U1449b
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    Packing:
    96T
    CLIA Kit for Rat Alpha-enolase
    Cat.:
    U1449m
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    Packing:
    96T
    CLIA Kit for Rat Alpha-enolase
    Cat.:
    U1449h
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    MSDS:
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    96T
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    CLIA Kit for Rat Alpha-enolase
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    U1449r
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    MSDS:
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    Packing:
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    Polyclonal Antibody for Rat Alpha-enolase
    Polyclonal Antibody for Rat Alpha-enolase
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    P1449Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Alpha-enolase
    Cat.:
    P1449Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Alpha-enolase
    Polyclonal Antibody for Rat Alpha-enolase
    Cat.:
    P1449Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Alpha-enolase
    Monoclonal Antibody for Rat Alpha-enolase
    Monoclonal Antibody for Rat Alpha-enolase
    Monoclonal Antibody for Rat Alpha-enolase
    Monoclonal Antibody for Rat Alpha-enolase
    Protein for Rat Alpha-enolase
    Protein for Rat Alpha-enolase
    Protein for Rat Alpha-enolase
    Protein for Rat Alpha-enolase
    Protein for Rat Alpha-enolase

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning and the nucleotide sequence of cDNA to mRNA for non-neuronal enolase (alpha alpha enolase) of rat brain and liver."
      Sakimura K. , Kushiya E. , Obinata M. , Takahashi Y.
      Nucleic Acids Res.13:4365-4378(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
      tissue: Brain.
      tissue: Liver.
    2. 2.
      Takahashi Y.
      Submitted (1986-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
      tissue: Pituitary.
      tissue: Testis.
    4. 4.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Kang S.U.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 10-28; 33-50; 72-103; 106-120; 163-179; 184-193; 203-228; 234-262; 270-281; 307-326; 336-394 AND 407-420;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
      tissue: Hippocampus.
      tissue: Spinal cord.
    5. 5.
      "Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane."
      Nakajima K. , Hamanoue M. , Takemoto N. , Hattori T. , Kato K. , Kohsaka S.
      J. Neurochem.63:2048-2057(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 46-57; 97-109; 245-262 AND 369-382;INTERACTION WITH PLG
      tissue: Embryonic brain.
    6. 6.
      "Rat cDNA encoding alpha enolase (2-phospho-D-glycerate hydro-lyase) (non-neural enolase) (NNE)."
      Bole-Feysot C. , Kelly P.A.
      Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 93-153
      tissue: Lymphoma.
    7. 7.
      "Differential expression of alpha- and beta-enolase genes during rat heart development and hypertrophy."
      Keller A. , Rouzeau J.-D. , Farhadian F. , Wisnewsky C. , Marotte F. , Lamande N. , Samuel J.L. , Schwartz K. , Lazar M. , Lucas M.
      Am. J. Physiol.269:H1843-H1851(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    8. 8.
      "Thyroid hormones differentially modulate enolase isozymes during rat skeletal and cardiac muscle development."
      Merkulova T. , Keller A. , Oliviero P. , Marotte F. , Samuel J.L. , Rappaport L. , Lamande N. , Lucas M.
      Am. J. Physiol.278:E330-E339(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    9. 9.
      "Localization of enolase in synaptic plasma membrane as an alphagamma heterodimer in rat brain."
      Ueta H. , Nagasawa H. , Oyabu-Manabe Y. , Toida K. , Ishimura K. , Hori H.
      Neurosci. Res.48:379-386(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION OF ALPHA/GAMMA HETERODIMER
    10. 10.
      "Identification of novel immunodominant epididymal sperm proteins using combinatorial approach."
      Khan S.A. , Suryawanshi A.R. , Ranpura S.A. , Jadhav S.V. , Khole V.V.
      Reproduction138:81-93(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;TISSUE SPECIFICITY
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