Entpd5 ELISA Kit for Mouse(Mus musculus) | EIAab.comEntpd5 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Entpd5(Gene name) > Mouse

Entpd5 (Gene name),

Ectonucleoside triphosphate diphosphohydrolase 5 (Protein name ), ENTP5_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Entpd5(Cd39l4);

Protein name:

Ectonucleoside triphosphate diphosphohydrolase 5(NTPDase 5);

Alternative:

ER-UDPase;CD39 antigen-like 4;Nucleoside diphosphatase;3.6.1.42;Guanosine-diphosphatase ENTPD5(GDPase ENTPD5);Uridine-diphosphatase ENTPD5(UDPase ENTPD5);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Subcellular Location:

Endoplasmic reticulum lumen

Protein Attributes:

Sequence length:

427

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

427:

TKKVNNIETG | WALGATFHLL | QSLGITS

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

Q9WUZ9

KEGG:

mmu:12499

Pfam:

PF01150

SMR:

Q9WUZ9

UniGene:

Mm.10211

Uniprot:

Q9WUZ9

FOR

ELISA Kit for Mouse NTPDase 5

Cat.:

E1978h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse NTPDase 5

Cat.:

E1978r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse NTPDase 5

Cat.:

E1978m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse NTPDase 5

Cat.:

E1978b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse NTPDase 5

Cat.:

E1978c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse NTPDase 5

Cat.:

U1978m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse NTPDase 5

Cat.:

U1978h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse NTPDase 5

Cat.:

U1978r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse NTPDase 5

Cat.:

U1978c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse NTPDase 5

Cat.:

U1978b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse NTPDase 5

Cat.:

P1978Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse NTPDase 5

Cat.:

P1978Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse NTPDase 5

Cat.:

P1978Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse NTPDase 5

Protein for Mouse NTPDase 5

Cat.:

R1978m

Price:

Please sign in first.

Packing:

1mg

Purity:

>90%

Protein for Mouse NTPDase 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases."
Chadwick B.P. , Williamson J. , Sheer D. , Frischauf A.-M.
Mamm. Genome9:162-164(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Testis.
2.

"Glycoprotein reglucosylation and nucleotide sugar utilization in the secretory pathway: identification of a nucleoside diphosphatase in the endoplasmic reticulum."
Trombetta E.S. , Helenius A.
EMBO J.18:3282-3292(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;GLYCOSYLATION;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES
tissue: Liver.
3.

"cDNA isolation, expression, and chromosomal localization of the mouse pcph proto-oncogene."
Recio J.A. , Zambrano N. , de La Pena L. , Powers C. , Siwarski D. , Huppi K. , Notario V.
Mol. Carcinog.26:130-136(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J.
tissue: Thymus.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
strain: NOD.
tissue: Bone.
tissue: Corpora quadrigemina.
tissue: Head.
tissue: Kidney.
tissue: Testis.
tissue: Thymus.
tissue: Urinary bladder.
5.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Kidney.
7.

"Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest."
Read R. , Hansen G. , Kramer J. , Finch R. , Li L. , Vogel P.
Vet. Pathol.46:491-504(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
8.

"The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway."
Fang M. , Shen Z. , Huang S. , Zhao L. , Chen S. , Mak T.W. , Wang X.
Cell143:711-724(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;GLYCOSYLATION;SUBCELLULAR LOCATION;INDUCTION;MUTAGENESIS OF GLU-171

Product Feedback Wall

* Email:
*Comments: