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Index > Protein center > Eps15l1(Gene name) > Mouse
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  • Eps15l1 (Gene name),
  • Epidermal growth factor receptor substrate 15-like 1 (Protein name ),  EP15R_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Eps15l1(Eps15-rs;Eps15R);
    Protein name:
    Epidermal growth factor receptor substrate 15-like 1;
    Alternative:
    Eps15-related protein(Eps15R);Epidermal growth factor receptor pathway substrate 15-related sequence(Eps15-rs);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).
    Function:
    Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Nucleus Membrane coated pit Localized to plasma membrane coated pits.
    Protein Attributes:
    Sequence length:
    907
    Sequence:
    50:
    MAAPLVPLSQ | QIPGGNPLYE | SYYKQVDPAY | TGRVGASEAA | LFLKKSGLSD | 
    100:
    IILGKIWDLA | DPEGKGFLDK | QGFYVALRLV | ACAQSGHEVT | LSSLSLTMPP | 
    150:
    PKFHDTSSPL | MATQSSAETH | WAVRVEEKAK | FDGIFESLLP | VNGLLSGDKV | 
    200:
    KPVLMNSKLP | LDVLGRVWDL | SDIDKDGHLD | RDEFAVAMHL | VYRALEKEPV | 
    250:
    PSILPPPLIP | PSKRKKTVFA | GAVPVLPASP | PPKDSLRSTP | SHGSVSSLNS | 
    300:
    TGSLSPKHSV | KQPPVAWVVP | VADKMRFDEI | FLKTDLDLDG | YVSGQEVKEI | 
    350:
    FMHSGLTQNL | LAHIWALADT | RQTGKLSKEQ | FALAMYFIQQ | KVSKGIDPPQ | 
    400:
    VLSPDMVPPS | ERGTPIPDSS | STLASGEFTG | VKELDDISQE | IAQLQREKYS | 
    450:
    LEQDIREKEE | AIRQKTSEVQ | ELQNDLDRET | SSLQELEAQK | QDAQDRLDEM | 
    500:
    DQQKAKLRDM | LSDVRQKCQD | ETQTISSLKT | QIQSQESDLK | SQEDDLNRAK | 
    550:
    SELNRLQQEE | TQLEQSIQAG | RAQLETILRS | LKCTQDDINQ | ARSKLSQLQE | 
    600:
    SHLEAHRSLE | QYDQVPDGVS | GTSLPDLATL | NEGILLAERG | GFGAMDDPFK | 
    650:
    NKALLFSNNS | QELHPDPFQA | EDPFKSDPFK | GADPFKGDPF | QSDPFSEQQT | 
    700:
    AATDPFGGDP | FKESDPFHSS | SSDDFFKKQT | KNDPFTSDPF | TKNPSLPSKL | 
    750:
    DPFESSDPFS | SSSISSKGSD | PFGTLDPFGS | SSFSSAEGFA | DFSQMSKPPP | 
    800:
    SGPFSSSLGG | TGFSDDPFKS | KQDTPALPPK | KPAPPRPKPP | SGQSTPVSQL | 
    850:
    GSSDFPESPD | PFQPLGADSG | DPFQNKKGFG | DPFSGKDPFA | PSSSAKPPKT | 
    900:
    SSSGFADFTS | FGNEEQQLAW | AKRESEKAEQ | ERLARLRRQE | QEDLELAIAL | 
    907:
    SKADMPA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Epidermal growth factor receptor substrate 15-like 1
    ELISA Kit for Mouse Epidermal growth factor receptor substrate 15-like 1
    CLIA Kit for Mouse Epidermal growth factor receptor substrate 15-like 1
    CLIA Kit for Mouse Epidermal growth factor receptor substrate 15-like 1
    Polyclonal Antibody for Mouse Epidermal growth factor receptor substrate 15-like 1
    Polyclonal Antibody for Mouse Epidermal growth factor receptor substrate 15-like 1
    Monoclonal Antibody for Mouse Epidermal growth factor receptor substrate 15-like 1
    Monoclonal Antibody for Mouse Epidermal growth factor receptor substrate 15-like 1
    Protein for Mouse Epidermal growth factor receptor substrate 15-like 1
    Protein for Mouse Epidermal growth factor receptor substrate 15-like 1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution."
      Wong W.T. , Schumacher C. , Salcini A.E. , Romano A. , Castagnino P. , Pelicci P.G. , Di Fiore P.
      Proc. Natl. Acad. Sci. U.S.A.92:9530-9534(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4)
      strain: C57BL/6J.
      tissue: Bone.
      tissue: Bone marrow.
      tissue: Kidney.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Kidney.
    5. 5.
      "Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization."
      Coda L. , Salcini A.E. , Confalonieri S. , Pelicci G. , Sorkina T. , Sorkin A. , Pelicci P.G. , Di Fiore P.P.
      J. Biol. Chem.273:3003-3012(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION;INTERACTION WITH EPS15; AP-2 COMPLEX; AGFG1 AND AGFG2
    6. 6.
      "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
      Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-562;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-74;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    8. 8.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-244 AND SER-255;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    10. 10.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "FCHo proteins are nucleators of clathrin-mediated endocytosis."
      Henne W.M. , Boucrot E. , Meinecke M. , Evergren E. , Vallis Y. , Mittal R. , McMahon H.T.
      Science328:1281-1284(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FCHO2
    12. 12.
      "The clathrin adaptor Dab2 recruits EH domain scaffold proteins to regulate integrin beta1 endocytosis."
      Teckchandani A. , Mulkearns E.E. , Randolph T.W. , Toida N. , Cooper J.A.
      Mol. Biol. Cell23:2905-2916(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB2
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