EPHA3 ELISA Kit for Chicken(Gallus gallus) | EIAab.comEPHA3 ELISA Kit for Chicken(Gallus gallus)

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Index > Protein center > EPHA3(Gene name) > Chicken

EPHA3 (Gene name),

Ephrin type-A receptor 3 (Protein name ), EPHA3_CHICK from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EPHA3(CEK4;ETK1);

Protein name:

Ephrin type-A receptor 3;

Alternative:

Tyrosine-protein kinase receptor ETK1;EPH-like kinase 4(EK4;cEK4);

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses.

Function:

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

983

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983:

MKKVGVTVVG | PQKKIVSSIK | TLETHTKNSP | VPV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9031.ENSGALP00000024798

UniGene:

Gga.805

Pfam:

PF01404

SMR:

P29318

KEGG:

gga:396402

Pfam:

PF14575

String:

P29318

Uniprot:

P29318

FOR

ELISA Kit for Chicken Ephrin type-A receptor 3

Cat.:

E1114c

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Packing:

96T

ELISA Kit for Chicken Ephrin type-A receptor 3

Cat.:

E1114r

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96T

ELISA Kit for Chicken Ephrin type-A receptor 3

Cat.:

E1114h

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96T

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ELISA Kit for Chicken Ephrin type-A receptor 3

Cat.:

E1114m

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96T

CLIA Kit for Chicken Ephrin type-A receptor 3

Cat.:

U1114h

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96T

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CLIA Kit for Chicken Ephrin type-A receptor 3

Cat.:

U1114c

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96T

CLIA Kit for Chicken Ephrin type-A receptor 3

Cat.:

U1114r

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MSDS:

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Packing:

96T

CLIA Kit for Chicken Ephrin type-A receptor 3

Cat.:

U1114m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Chicken Ephrin type-A receptor 3

Cat.:

P1114Rb-r

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40ug/0.2ml

Polyclonal Antibody for Chicken Ephrin type-A receptor 3

Cat.:

P1114Rb-m

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40ug/0.2ml

Polyclonal Antibody for Chicken Ephrin type-A receptor 3

Cat.:

P1114Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Chicken Ephrin type-A receptor 3

Protein for Chicken Ephrin type-A receptor 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of a new eph-related receptor tyrosine kinase gene from mouse and chicken that is developmentally regulated and encodes at least two forms of the receptor."
Sajjadi F.G. , Pasquale E.B. , Subramani S.
New Biol.3:769-778(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Loss-of-function analysis of EphA receptors in retinotectal mapping."
Feldheim D.A. , Nakamoto M. , Osterfield M. , Gale N.W. , DeChiara T.M. , Rohatgi R. , Yancopoulos G.D. , Flanagan J.G.
J. Neurosci.24:2542-2550(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN RETINOTECTAL MAPPING

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