Clathrin interactor 1 (Protein name
), EPN4_HUMAN from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
CLINT1(ENTH;EPN4;EPNR;KIAA0171);
Protein name:
Clathrin interactor 1;
Alternative:
Enthoprotin;Clathrin-interacting protein localized in the trans-Golgi region(Clint);Epsin-related protein(EpsinR);Epsin-4;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds clathrin heavy chain, GGA2, AP-2 and AP1G1.
Function:
Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Subcellular Location:
Cytoplasm
Cytoplasm
perinuclear region
Membrane
Peripheral membrane protein
Cytoplasmic vesicle
clathrin-coated vesicle
Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];PROTEIN SEQUENCE OF 14-27; 30-49; 110-129; 134-146; 157-171; 201-218; 248-274 AND 284-297 (ISOFORM 1);IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH CLATHRIN; AP1G1 AND GGA2;SUBCELLULAR LOCATION
2.
"KIAA0171 as a new member (epsin 4) of the epsin family." Hong W.
Submitted (2001-10) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
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Cited for: FUNCTION;MUTAGENESIS OF 423-LEU--LEU-426;INTERACTION WITH CLATHRIN; AP1G1 AND AP-2;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
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Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MUTAGENESIS OF ASP-34; ASP-349; ASP-371 AND ASP-422;INTERACTION WITH AP1G1; AP-2 AND CLATHRIN
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-227;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-245 AND SER-299;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-245 AND SER-299;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-227;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-299;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-245 AND SER-299;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-299;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
Vaild Sequence:
