Gene name:
ERC2 (KIAA0378) ;
Protein name:
ERC protein 2 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with BSN, ERC1, PPFIA1, PPFIA2, PPFIA3 and PPFIA4. Interacts through its C-terminus with the PDZ domain of RIMS1. Part of a complex consisting of ERC2, RIMS1 and UNC13A.
Function:
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Subcellular Location:
Cytoplasm
Cell junction
synapse
Cell junction
synapse
synaptosome
Cytoplasm
cytoskeleton
In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density.
Protein Attributes:
50:
MYGSARTITN | LEGSPSRSPR | LPRSPRLGHR | RTSSGGGGGT | GKTLSMENIQ |
100:
SLNAAYATSG | PMYLSDHEGV | ASTTYPKGTM | TLGRATNRAV | YGGRVTAMGS |
150:
SPNIASAGLS | HTDVLSYTDQ | HGGLTGSSHH | HHHQVPSMLR | QVRDSTMLDL |
200:
QAQLKELQRE | NDLLRKELDI | KDSKLGSSMN | SIKTFWSPEL | KKERVLRKEE |
250:
AARMSVLKEQ | MRVSHEENQH | LQLTIQALQD | ELRTQRDLNH | LLQQESGNRG |
300:
AEHFTIELTE | ENFRRLQAEH | DRQAKELFLL | RKTLEEMELR | IETQKQTLNA |
350:
RDESIKKLLE | MLQSKGLPSK | SLEDDNERTR | RMAEAESQVS | HLEVILDQKE |
400:
KENIHLREEL | HRRSQLQPEP | AKTKALQTVI | EMKDTKIASL | ERNIRDLEDE |
450:
IQMLKANGVL | NTEDREEEIK | QIEVYKSHSK | FMKTKIDQLK | QELSKKESEL |
500:
LALQTKLETL | SNQNSDCKQH | IEVLKESLTA | KEQRAAILQT | EVDALRLRLE |
550:
EKESFLNKKT | KQLQDLTEEK | GTLAGEIRDM | KDMLEVKERK | INVLQKKIEN |
600:
LQEQLRDKDK | QLTNLKDRVK | SLQTDSSNTD | TALATLEEAL | SEKERIIERL |
650:
KEQRERDDRE | RLEEIESFRK | ENKDLKEKVN | ALQAELTEKE | SSLIDLKEHA |
700:
SSLASAGLKR | DSKLKSLEIA | IEQKKEECSK | LEAQLKKAHN | IEDDSRMNPE |
750:
FADQIKQLDK | EASYYRDECG | KAQAEVDRLL | EILKEVENEK | NDKDKKIAEL |
800:
ESLTLRHMKD | QNKKVANLKH | NQQLEKKKNA | QLLEEVRRRE | DSMADNSQHL |
850:
QIEELMNALE | KTRQELDATK | ARLASTQQSL | AEKEAHLANL | RIERRKQLEE |
900:
ILEMKQEALL | AAISEKDANI | ALLELSASKK | KKTQEEVMAL | KREKDRLVHQ |
950:
LKQQTQNRMK | LMADNYDDDH | HHYHHHHHHH | HHRSPGRSQH | SNHRPSPDQD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human ERC protein 2
ELISA Kit for Human ERC protein 2
ELISA Kit for Human ERC protein 2
CLIA Kit for Human ERC protein 2
CLIA Kit for Human ERC protein 2
CLIA Kit for Human ERC protein 2
Polyclonal Antibody for Human ERC protein 2
Polyclonal Antibody for Human ERC protein 2
Polyclonal Antibody for Human ERC protein 2
Monoclonal Antibody for Human ERC protein 2
Monoclonal Antibody for Human ERC protein 2
Monoclonal Antibody for Human ERC protein 2
Protein for Human ERC protein 2
Protein for Human ERC protein 2
Protein for Human ERC protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
PNS .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INTERACTION WITH PPFIA1; PPFIA2; PPFIA3 AND PPFIA4