Erc2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comErc2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Erc2(Gene name) > Rat

Erc2 (Gene name),

ERC protein 2 (Protein name ), ERC2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Erc2(Cast1;Cmbp);

Protein name:

ERC protein 2;

Alternative:

Cytomatrix protein p110;CAZ-associated structural protein 1(CAST1;Cast);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with BSN, ERC1, PPFIA1, PPFIA2, PPFIA3 and PPFIA4. Interacts through its C-terminus with the PDZ domain of RIMS1. Part of a complex consisting of ERC2, RIMS1 and UNC13A.

Function:

Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.

Subcellular Location:

Cytoplasm Cell junction synapse Cell junction synapse synaptosome Cytoplasm cytoskeleton Localized to the active zone of presynaptic density. Colocalizes with RIMS1 and BSN in early stages of synapse formation.

Protein Attributes:

Sequence length:

957

Sequence:

50:

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650:

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850:

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950:

957:

DEEGIWA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8K3M6

UniGene:

Rn.213719

KEGG:

rno:259269

Pfam:

PF10174

Uniprot:

Q8K3M6

FOR

ELISA Kit for Rat ERC protein 2

CLIA Kit for Rat ERC protein 2

Polyclonal Antibody for Rat ERC protein 2

Monoclonal Antibody for Rat ERC protein 2

Protein for Rat ERC protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and Munc13-1."
Ohtsuka T. , Takao-Rikitsu E. , Inoue E. , Inoue M. , Takeuchi M. , Matsubara K. , Deguchi-Tawarada M. , Satoh K. , Morimoto K. , Nakanishi H. , Takai Y.
J. Cell Biol.158:577-590(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INTERACTION WITH RIMS1 AND BSN;IDENTIFICATION IN A COMPLEX WITH RIMS1 AND UNC13A
strain: Sprague-Dawley.
2.

"A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones."
Wang Y. , Liu X. , Biederer T. , Suedhof T.C.
Proc. Natl. Acad. Sci. U.S.A.99:14464-14469(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

Lubec G. , Chen W.-Q. , Kang S.U. , Lubec S.
Submitted (2007-09) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-17; 276-281; 332-349; 373-383; 406-420; 447-456; 485-496; 521-528; 547-556; 629-659; 666-674; 729-734; 779-787 AND 856-879;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Brain.
tissue: Hippocampus.
4.

"CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST."
Deguchi-Tawarada M. , Inoue E. , Takao-Rikitsu E. , Inoue M. , Ohtsuka T. , Takai Y.
Genes Cells9:15-23(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ERC1
strain: Sprague-Dawley.

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