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Index > Protein center > Eps8l1(Gene name) > Mouse
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  • Eps8l1 (Gene name),
  • Epidermal growth factor receptor kinase substrate 8-like protein 1 (Protein name ),  ES8L1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Eps8l1(Eps8r1);
    Protein name:
    Epidermal growth factor receptor kinase substrate 8-like protein 1(EPS8-like protein 1);
    Alternative:
    Epidermal growth factor receptor pathway substrate 8-related protein 1(EPS8-related protein 1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.
    Function:
    Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    716
    Sequence:
    50:
    MSTTTGPEAA | PKPSAKSIYE | QRKRYSTVVM | ADVSQYHVNH | LVTFCLGEED | 
    100:
    GVHTVEDASR | KLAVMDSQGR | VWAQEMLLRV | SPSQVTLLDP | VSKEELESYP | 
    150:
    LDAIVRCDAV | MPRGRSRSLL | LLVCQEPERA | QPDVHFFQGL | LLGAELIRED | 
    200:
    IQGALQNYRS | GRGERRAAAL | RATQEELRRG | ASPAAETPPL | QRRPSVRLVI | 
    250:
    NTVEPSAVRG | RPQVESIPET | EEARKPDQAR | TTSSADPTSP | DLGPRGPELA | 
    300:
    GLQAERDVDI | LNHVFDDVES | FVSRLQKSAE | ATRVLEHRER | GRRTRRRAAG | 
    350:
    EGLLTLRAKP | PTEAEYTDVL | QKIKYAFSLL | ARLRGNIANP | SSPELLHFLF | 
    400:
    GPLQMIVNTS | GGPEFAKSVR | RPHLTLEAVT | LLRDNVTPGE | NELWTSLGDS | 
    450:
    WTCPGVELPP | EEGSPYSPEF | YNGWEPPATD | PQGRPWEDPV | EKQLQHEKRR | 
    500:
    RQQSAPQVAV | NGQQDPELET | ESQLEEKARK | WVLCNYDFQA | RNGSELSVKH | 
    550:
    RDVLEVLDDR | RKWWKVRDHQ | GQEGYVPYNI | LTPHPGPQVH | RSQSPARHLE | 
    600:
    TSTPPPPPAP | APAPTQVRPQ | WDSCDSLNSL | DPSEKEKFSQ | MLCVNEELQS | 
    650:
    RLAQGRSGPS | RVTPGPRAQE | PQLSPRSEAS | VVRAWLQTKG | FSSGTVEALG | 
    700:
    VLTGAQLFSL | QKEELRAVCP | EEGARVYSQV | TVQRALLEDR | EKVSELEAVM | 
    716:
    EKQKKKVEGE | TKTEVI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse EPS8-like protein 1
    ELISA Kit for Mouse EPS8-like protein 1
    CLIA Kit for Mouse EPS8-like protein 1
    CLIA Kit for Mouse EPS8-like protein 1
    Polyclonal Antibody for Mouse EPS8-like protein 1
    Polyclonal Antibody for Mouse EPS8-like protein 1
    Monoclonal Antibody for Mouse EPS8-like protein 1
    Monoclonal Antibody for Mouse EPS8-like protein 1
    Protein for Mouse EPS8-like protein 1
    Protein for Mouse EPS8-like protein 1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure."
      Tocchetti A. , Confalonieri S. , Scita G. , Di Fiore P.P. , Betsholtz C.
      Genomics81:234-244(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Skin.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Retina.
    4. 4.
      "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway."
      Offenhaeuser N. , Borgonovo A. , Disanza A. , Romano P. , Ponzanelli I. , Iannolo G. , Di Fiore P.P. , Scita G.
      Mol. Biol. Cell15:91-98(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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