Espn ELISA Kit for Rat(Rattus norvegicus) | EIAab.comEspn ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Espn(Gene name) > Rat

Espn (Gene name),

Espin (Protein name ), ESPN_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Espn;

Protein name:

Espin;

Alternative:

Ectoplasmic specialization protein;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer (By similarity). Interacts with PFN2 (By similarity). Binds F-actin in a Ca(2+)-resistant fashion. Interacts (via N-terminal) with BAIAP2 (via SH3-domain).

Function:

Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells.

Subcellular Location:

Isoform 8 Cytoplasm cytoskeleton Cell projection dendritic spine

Protein Attributes:

Sequence length:

837

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

837:

IQRAKEQSEK | LRTLGYDEAK | LAPWQRQVIL | KKGEIPK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q63618

Pfam:

PF00023

UniGene:

Rn.91373

KEGG:

rno:56227

Uniprot:

Q63618

FOR

ELISA Kit for Rat Espin

CLIA Kit for Rat Espin

Polyclonal Antibody for Rat Espin

Monoclonal Antibody for Rat Espin

Protein for Rat Espin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations."
Bartles J.R. , Wierda A. , Zheng L.
J. Cell Sci.109:1229-1239(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 20-39; 556-568; 662-684; 775-779 AND 820-822;INTERACTION WITH F-ACTIN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
2.

"Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli."
Bartles J.R. , Zheng L. , Li A. , Wierda A. , Chen B.
J. Cell Biol.143:107-119(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBUNIT;INTERACTION WITH F-ACTIN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: Sprague-Dawley.
tissue: Kidney.
3.

"Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53."
Sekerkova G. , Loomis P.A. , Changyaleket B. , Zheng L. , Eytan R. , Chen B. , Mugnaini E. , Bartles J.R.
J. Neurosci.23:1310-1319(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3; 4; 6 AND 8);TISSUE SPECIFICITY;SUBCELLULAR LOCATION;INTERACTION WITH BAIAP2
strain: Sprague-Dawley.
tissue: Cerebellum.
4.

"Espins are multifunctional actin cytoskeletal regulatory proteins in the microvilli of chemosensory and mechanosensory cells."
Sekerkova G. , Zheng L. , Loomis P.A. , Changyaleket B. , Whitlon D.S. , Mugnaini E. , Bartles J.R.
J. Neurosci.24:5445-5456(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 5 AND 7);TISSUE SPECIFICITY
strain: Sprague-Dawley.

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